Institute of Special Economic Animal and Plant Science, Chinese Academy of Agricultural Sciences, Changchun 130112, China.
Environ Toxicol Pharmacol. 2013 Jan;35(1):82-7. doi: 10.1016/j.etap.2012.11.009. Epub 2012 Nov 26.
Aluminum (Al) is widely used in daily life and will lead to environmental release and exposure. The toxicity of Al had been documented, and which attracted a growing concern on human and animal health. The immune system appears to be sensitive to Al exposure. But few studies focused on the potential immunological responses induced by Al. It is imperative to study the effects of Al on the immune function and this review discusses the effects of Al on autoimmunity, oral tolerance, expression of the immune cells, hypersensitivity and erythrocyte immune function. It will provide evidence to study the association between Al and immune function.
铝（Al）在日常生活中被广泛应用，这将导致其向环境中的释放和暴露。铝的毒性已经得到证实，这引起了人们对人类和动物健康的日益关注。免疫系统似乎对铝暴露敏感。但是，很少有研究关注铝引起的潜在免疫反应。研究铝对免疫功能的影响至关重要，本综述讨论了铝对自身免疫、口服耐受、免疫细胞表达、过敏反应和红细胞免疫功能的影响。这将为研究铝与免疫功能之间的关系提供证据。
