Partnerships in Prevention Science Institute, Iowa State University, 2625 N Loop Drive, Suite 2400, Ames, IA 50010, USA.
Prev Med. 2013 Mar;56(3-4):190-6. doi: 10.1016/j.ypmed.2012.12.013. Epub 2012 Dec 28.
To examine the effects of a delivery system for evidence-based preventive interventions through 12th grade, 6.5 years past baseline.
A cohort sequential design included 28 public school districts randomly assigned to the partnership delivery system or usual-programming conditions. At baseline, 11,960 students participated. Partnerships supported community teams that implemented a family-focused intervention in 6th grade and a school-based intervention in 7th grade. Outcome measures included lifetime, current misuse, and frequencies of misuse, for a range of substances. Intent-to-treat, multilevel analyses of covariance of point-in-time misuse and analyses of growth in misuse were conducted.
Results showed significantly lower substance misuse in the intervention group at one or both time points for most outcomes, with relative reduction rates of up to 31.4%. There was significantly slower growth in misuse in the intervention group for 8 of the 10 outcomes. In addition, risk moderation results indicated that there were significantly greater intervention benefits for higher- versus lower-risk youth, for the misuse of 6 of the 10 substances at 11th grade, illicit substances at 12th grade, and growth in the misuse of illicit substances.
Partnership-based delivery systems for brief universal interventions have potential for public health impact by reducing substance misuse among youth, particularly higher-risk youth.
通过 12 年级，即基线后 6.5 年，考察一种基于证据的预防干预措施的传递系统的效果。
一项队列序贯设计包括 28 个公立学区，随机分配到合作传递系统或常规编程条件下。基线时，有 11960 名学生参与。合作关系支持社区团队，在 6 年级实施以家庭为中心的干预措施，在 7 年级实施基于学校的干预措施。结果测量包括终生、当前和误用频率，涉及多种物质。进行了即时误用的意向治疗、多层次协方差分析和误用增长的分析。
结果表明，在大多数结果中，干预组在一个或两个时间点的物质滥用明显较低，相对减少率高达 31.4%。干预组在 10 项结果中的 8 项中误用的增长明显较慢。此外，风险调节结果表明，对于高风险和低风险的青少年来说，干预的益处明显更大，对于 11 年级的 10 种物质中的 6 种、12 年级的非法物质以及非法物质滥用的增长。
基于合作的简短普遍干预措施的传递系统具有通过减少青少年，特别是高风险青少年的物质滥用，对公共卫生产生影响的潜力。
