Stanley Research Center, Sheppard Pratt Health System, 6501 North Charles St., Baltimore, MD 21204, USA.
Psychiatr Serv. 2013 Jan;64(1):44-50. doi: 10.1176/appi.ps.201200143.
This study examined the prevalence of cigarette smoking and the quantity of cigarettes consumed by individuals with schizophrenia or bipolar disorder and by those with no psychiatric disorder in the period 1999-2011.
A total of 991 individuals with schizophrenia, bipolar disorder, or no psychiatric illness provided information about their cigarette smoking at recruitment into a research study for which they were selected without regard to their smoking status. Differences among groups and trends over time among new enrollees were examined with multivariate models. Regression analyses were used to compare smoking between the schizophrenia and bipolar disorder groups.
There were marked differences in the prevalence of smoking and in the quantity of cigarettes consumed among the diagnostic groups. Overall, 64% of individuals with schizophrenia, 44% with bipolar disorder, and 19% without psychiatric illness reported that they were current smokers. These group differences remained fairly constant over the observation period, and there were no statistically significant time trends in smoking or cigarette consumption after adjustment for demographic covariates. Within the psychiatric illness groups, smoking and cigarette consumption were significantly associated with less education, a history of substance abuse, longer illness duration, Caucasian race, and schizophrenia diagnosis but not with psychiatric symptom severity.
The prevalence of smoking has remained alarmingly high among individuals with schizophrenia and bipolar disorder in routine psychiatric settings. Concerted efforts are urgently needed to promote smoking cessation in these groups.
本研究调查了 1999 年至 2011 年间,精神分裂症或双相情感障碍患者与无精神疾病个体的吸烟流行率和吸烟量。
共有 991 名精神分裂症、双相情感障碍或无精神疾病的个体在参加一项研究时提供了关于他们吸烟情况的信息,他们是在不考虑吸烟状况的情况下被选中的。采用多元模型比较了组间差异和新入组者的时间趋势。回归分析用于比较精神分裂症和双相情感障碍组之间的吸烟情况。
在诊断组之间,吸烟的流行率和吸烟量存在显著差异。总体而言,64%的精神分裂症患者、44%的双相情感障碍患者和 19%的无精神疾病个体报告他们是当前吸烟者。这些组间差异在整个观察期间基本保持不变,并且在调整人口统计学协变量后,吸烟或吸烟量没有统计学意义的时间趋势。在精神疾病组内,吸烟和吸烟量与受教育程度较低、物质滥用史、较长的疾病持续时间、白种人种族和精神分裂症诊断显著相关,但与精神症状严重程度无关。
在常规精神科环境中,精神分裂症和双相情感障碍患者的吸烟流行率仍然高得令人震惊。迫切需要努力促进这些人群戒烟。