Department Organic Chemistry, Universidad Complutense de Madrid, Madrid, Spain.
Magn Reson Chem. 2012 Dec;50 Suppl 1:S80-5. doi: 10.1002/mrc.3888.
Solution nuclear magnetic resonance spectroscopy is especially useful in the carbohydrate field. The measurement of residual dipolar couplings provides long-range structural information, a valuable complement for the structural study of carbohydrates either in its free form or in the bound state to proteins. They permit to deduce the geometry and the flexibility of the glycosidic linkages, which have a major influence on the conformation of carbohydrates and their overall shape. This article reviews the current application of the residual dipolar couplings methodology to carbohydrates.
溶液核磁共振波谱学在碳水化合物领域特别有用。残磁偶合的测量提供了远程结构信息，这对于碳水化合物的结构研究，无论是在游离形式还是与蛋白质结合的状态下，都是一种有价值的补充。它们可以推断糖苷键的几何形状和柔韧性，这对碳水化合物的构象及其整体形状有重大影响。本文综述了残磁偶合方法在碳水化合物中的应用现状。
