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Influence of midazolam on the plasma concentrations of mepivacaine after lumbar epidural injection in children.

作者信息

Giaufre E, Bruguerolle B, Morisson-Lacombe G, Rousset-Rouviere B

机构信息

Surgical Pediatric Department, Saint-Joseph Fondation Hospital, Marseille, France.

出版信息

Eur J Clin Pharmacol. 1990;38(1):91-2. doi: 10.1007/BF00314812.

Abstract

Twenty children undergoing surgery received a lumbar block using 0.4 ml/kg mepivacaine 2.0%. They were randomized into two groups, one of which received midazolam 0.4 mg/kg rectally as premedication. Midazolam administration did not significantly influence the plasma concentrations of mepivacaine.

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