Department of Public Health, University of Tartu, Tartu, Estonia.
Int J Drug Policy. 2013 Jul;24(4):312-8. doi: 10.1016/j.drugpo.2012.11.002. Epub 2013 Jan 3.
Here we report a study aimed at estimating trends in the prevalence of injection drug use between 2005 and 2009 in Estonia.
Descriptions of behavioural epidemics have received little attention compared with infectious disease epidemics in Eastern Europe.
The number of injection drug users (IDUs) aged 15-44 each year between 2005 and 2009 was estimated using capture-recapture methodology based on 4 data sources (2 treatment data bases: drug use and non-fatal overdose treatment; criminal justice (drug related offences) and mortality (injection drug use related deaths) data). Poisson log-linear regression models were applied to the matched data, with interactions between data sources fitted to replicate the dependencies between the data sources. Linear regression was used to estimate average change over time.
There were 24305, 12,292, 238, 545 records and 8100, 1655, 155, 545 individual IDUs identified in the four capture sources (police, drug treatment, overdose, and death registry, accordingly) over the period 2005-2009. The estimated prevalence of IDUs among the population aged 15-44 declined from 2.7% (1.8-7.9%) in 2005 to 2.0% (1.4-5.0%) in 2008, and 0.9% (0.7-1.7%) in 2009. Regression analysis indicated an average reduction of about 1600 injectors per year.
While the capture-recapture method has known limitations, the results are consistent with other data from Estonia. Identifying the drivers of change in the prevalence of injection drug use warrants further research.
本研究旨在估计 2005 年至 2009 年期间爱沙尼亚注射吸毒者流行率的趋势。
与东欧传染病流行相比,行为流行的描述受到的关注较少。
2005 年至 2009 年期间,每年 15-44 岁的注射吸毒者(IDU)人数使用基于 4 个数据源(2 个治疗数据库:药物使用和非致命性药物过量治疗;刑事司法(与药物相关的犯罪)和死亡率(与注射药物使用相关的死亡))的捕获-再捕获方法进行估计。将泊松对数线性回归模型应用于匹配数据,并拟合数据源之间的相互作用,以复制数据源之间的依赖性。使用线性回归估计随时间的平均变化。
在 2005-2009 年期间,四个捕获源(相应地为警察、药物治疗、药物过量和死亡登记处)分别记录了 24305、12292、238、545 条记录和 8100、1655、155、545 名 IDU 个体。15-44 岁人群中 IDU 的估计流行率从 2005 年的 2.7%(1.8-7.9%)下降到 2008 年的 2.0%(1.4-5.0%)和 2009 年的 0.9%(0.7-1.7%)。回归分析表明,每年约有 1600 名注射者减少。
虽然捕获-再捕获方法存在已知的局限性,但结果与爱沙尼亚的其他数据一致。进一步研究需要确定注射吸毒流行率变化的驱动因素。