血浆和尿液中碘海醇的高效液相色谱测定法。
High-performance liquid chromatographic assay of iomeprol in plasma and urine.
作者信息
Lorusso V, Poggesi I, Dal Fiume D, Tirone P
机构信息
Bracco Research Department, Milan, Italy.
出版信息
J Chromatogr. 1990 Feb 23;525(2):401-9. doi: 10.1016/s0378-4347(00)83416-7.
A high-performance liquid chromatographic method for assaying the radiographic contrast agent iomeprol in plasma and urine samples is described. Before reversed-phase chromatography, the biological fluids are treated with ion-exchange resins and iopamidol is added as internal standard. The compounds are monitored during elution by ultraviolet-visible spectrometry at 245 nm. The method shows good precision and accuracy and gives similar results to X-ray fluorescence analysis.
描述了一种用于测定血浆和尿液样本中造影剂碘海醇的高效液相色谱法。在反相色谱之前，生物流体用离子交换树脂处理，并加入碘帕醇作为内标。在洗脱过程中通过245nm的紫外可见光谱法监测这些化合物。该方法显示出良好的精密度和准确性，并且给出了与X射线荧光分析相似的结果。
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