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与 HIV 和艾滋病相关的神经系统并发症:护理的临床意义。

Neurological complications associated with HIV and AIDS: clinical implications for nursing.

出版信息

J Neurosci Nurs. 2013 Feb;45(1):5-13. doi: 10.1097/JNN.0b013e318275b1b2.

DOI:10.1097/JNN.0b013e318275b1b2
PMID:23291867
Abstract

This article provides a clinical nursing update on major neurological complications associated with HIV and AIDS. Life expectancy for those with AIDS has increased as a consequence of antiretroviral therapy, and thus, neurological complications remain a clinical challenge. Four significant diseases associated with HIV and AIDS are addressed: HIV-associated dementia, peripheral neuropathy, cryptococcal meningitis, and toxoplasmosis. Updated statistics, a review of pathophysiology, common manifestations, diagnostic tests, and standard treatments are discussed for each disease. Nursing considerations when caring for this population are reviewed and include assessment, safety, activities of daily living, pain management, and treatment adherence.

摘要

本文提供了与 HIV 和艾滋病相关的主要神经并发症的临床护理更新。由于抗逆转录病毒疗法的应用,艾滋病患者的预期寿命有所延长,因此,神经并发症仍然是一个临床挑战。本文讨论了与 HIV 和艾滋病相关的四种重要疾病:HIV 相关性痴呆、周围神经病、隐球菌性脑膜炎和弓形体病。更新了每种疾病的统计数据、病理生理学、常见表现、诊断测试和标准治疗的回顾。本文还回顾了护理此类人群时的护理注意事项,包括评估、安全、日常生活活动、疼痛管理和治疗依从性。

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1
Neurological complications associated with HIV and AIDS: clinical implications for nursing.与 HIV 和艾滋病相关的神经系统并发症:护理的临床意义。
J Neurosci Nurs. 2013 Feb;45(1):5-13. doi: 10.1097/JNN.0b013e318275b1b2.
2
[Opportunistic infections--prevention and treatment].[机会性感染——预防与治疗]
Sidahora. 1995 Winter:42-7.
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HIV-1-related neurologic disorders. Neurosurgical implications.与人类免疫缺陷病毒1型(HIV-1)相关的神经系统疾病。神经外科方面的影响。
Neuroimaging Clin N Am. 1997 Aug;7(3):527-59.
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Incidence proportion of and risk factors for AIDS patients diagnosed with HIV dementia, central nervous system toxoplasmosis, and cryptococcal meningitis.被诊断患有人类免疫缺陷病毒痴呆症、中枢神经系统弓形虫病和隐球菌性脑膜炎的艾滋病患者的发病率及危险因素。
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Neurological complications of HIV infection.人类免疫缺陷病毒感染的神经系统并发症
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[Neurological manifestations associated with HIV-1 infection].
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Other neurological diseases in HIV-1 infection: clinical aspects.人类免疫缺陷病毒1型感染中的其他神经系统疾病:临床方面
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Neurologic conditions are difficult to treat.神经系统疾病难以治疗。
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Virol J. 2025 May 24;22(1):161. doi: 10.1186/s12985-025-02789-5.
2
Epidemiology and factors associated with peripheral neuropathy among HIV infected patients in Gondar, Ethiopia: A cross-sectional study.埃塞俄比亚贡德尔地区 HIV 感染患者周围神经病的流行病学及相关因素:一项横断面研究。
PLoS One. 2019 Jan 29;14(1):e0211354. doi: 10.1371/journal.pone.0211354. eCollection 2019.
3
Prevalence of peripheral neuropathy and its associated demographic and health status characteristics, among people on antiretroviral therapy in Rwanda.
卢旺达接受抗逆转录病毒治疗人群中周围神经病变的患病率及其相关人口统计学和健康状况特征
BMC Public Health. 2014 Dec 19;14:1306. doi: 10.1186/1471-2458-14-1306.