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本文引用的文献

1
Rotavirus vaccine series completion and adherence to vaccination schedules among infants in managed care in the United States.美国管理式医疗保健中婴儿轮状病毒疫苗系列接种完成率和疫苗接种计划依从性。
Vaccine. 2012 May 21;30(24):3717-22. doi: 10.1016/j.vaccine.2011.12.077. Epub 2011 Dec 31.
2
Imaging studies for low back pain.腰痛的影像学检查
J Pain Palliat Care Pharmacother. 2008;22(4):306-11. doi: 10.1080/15360280802537332.
3
National and state vaccination coverage among children aged 19-35 months--United States, 2010.2010 年美国 19-35 月龄儿童的国家和州疫苗接种覆盖率。
MMWR Morb Mortal Wkly Rep. 2011 Sep 2;60(34):1157-63.
4
Rotavirus vaccination coverage among infants aged 5 months - immunization information system sentinel sites, United States, June 2006-June 2009.轮状病毒疫苗接种覆盖率在 5 个月大婴儿-免疫信息系统监测点,美国,2006 年 6 月至 2009 年 6 月。
MMWR Morb Mortal Wkly Rep. 2010 May 7;59(17):521-4.
5
Reduction in acute gastroenteritis hospitalizations among US children after introduction of rotavirus vaccine: analysis of hospital discharge data from 18 US states.轮状病毒疫苗问世后美国儿童急性肠胃炎住院人数减少:来自 18 个美国州的医院出院数据分析。
J Infect Dis. 2010 Jun 1;201(11):1617-24. doi: 10.1086/652403.
6
Adoption of rotavirus vaccination by pediatricians and family medicine physicians in the United States.美国儿科医生和家庭医学医生对轮状病毒疫苗的采用情况。
Pediatrics. 2009 Nov;124(5):e809-16. doi: 10.1542/peds.2008-3832. Epub 2009 Oct 12.
7
Discovery of rotavirus: Implications for child health.轮状病毒的发现:对儿童健康的影响。
J Gastroenterol Hepatol. 2009 Oct;24 Suppl 3:S81-5. doi: 10.1111/j.1440-1746.2009.06076.x.
8
Rotaviruses: from pathogenesis to vaccination.轮状病毒:从发病机制到疫苗接种
Gastroenterology. 2009 May;136(6):1939-51. doi: 10.1053/j.gastro.2009.02.076. Epub 2009 May 7.
9
Prevention of rotavirus gastroenteritis among infants and children: recommendations of the Advisory Committee on Immunization Practices (ACIP).婴幼儿轮状病毒胃肠炎的预防:免疫实践咨询委员会(ACIP)的建议
MMWR Recomm Rep. 2009 Feb 6;58(RR-2):1-25.
10
Burden of rotavirus disease among children visiting pediatric emergency departments in Cincinnati, Ohio, and Oakland, California, in 1999-2000.1999 - 2000年俄亥俄州辛辛那提市和加利福尼亚州奥克兰市儿科急诊科就诊儿童的轮状病毒疾病负担。
Pediatrics. 2008 Nov;122(5):971-7. doi: 10.1542/peds.2007-1609.

商业保险人群中轮状病毒疫苗接种质量措施的依从性。

Adherence to rotavirus vaccination quality measures in a commercially insured population.

机构信息

HealthCore, Inc.; Wilmington, DE USA.

出版信息

Hum Vaccin Immunother. 2013 Feb;9(2):389-97. doi: 10.4161/hv.22877. Epub 2013 Jan 4.

DOI:10.4161/hv.22877
PMID:23291933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3859762/
Abstract

BACKGROUND

This retrospective study determined the level of compliance to rotavirus vaccination guidelines within a large, commercially insured US population, as well as compliance with PI, ACIP and HEDIS measures for rotavirus vaccination.

METHODS

Medical and pharmacy claims were obtained from the HealthCore Integrated Research Database. Enrolled children were stratified into PI, ACIP and HEDIS cohorts. The PI cohort was subdivided into RV5 and RV1 cohorts due to the differences in dosing schedules and patients with mixed dosing were excluded from the these two cohorts. Patients identified in the HEDIS cohort were linked to the administering physicians.

RESULTS

Of 162,614 patients in PI cohort, 27% did not receive rotavirus vaccinations, 24% (RV5) and 15% (RV1) had incomplete doses (p < 0.0001; RV1 vs. RV5). A total of 76% of patients completed RV5 series but not on schedule, 54% completed on schedule. A total of 85% of patients completed the RV1 series at any time, 69% completed on schedule. Among health plans, 53% of patients completed the series, 22% (RV5) and 15% (RV1) had incomplete doses (p < 0.0001). Of 2,086 physicians who treated ≥ 10 patients within the plan (regardless of vaccination status), 78% had > 50% of patients complete, 22% had > 90% of patients completed.

CONCLUSION

Despite both two effective rotavirus vaccines and national immunization recommendations, rotavirus vaccination remains underutilized for infants.

摘要

背景

本回顾性研究旨在确定在美国大型商业保险人群中,轮状病毒疫苗接种指南的遵从程度,以及轮状病毒疫苗接种的 PI、ACIP 和 HEDIS 措施的遵从程度。

方法

从 HealthCore 综合研究数据库获取医疗和药房索赔。将入组儿童分为 PI、ACIP 和 HEDIS 队列。由于给药方案的差异,PI 队列分为 RV5 和 RV1 队列,并且混合剂量的患者被排除在这两个队列之外。HEDIS 队列中的患者与负责接种的医生相关联。

结果

在 PI 队列的 162614 名患者中,27%未接受轮状病毒疫苗接种,24%(RV5)和 15%(RV1)未完成全剂量接种(p<0.0001;RV1 与 RV5 相比)。76%的患者完成了 RV5 系列接种,但未按计划完成,54%的患者按计划完成。85%的患者在任何时候都完成了 RV1 系列接种,69%的患者按计划完成。在不同的健康计划中,53%的患者完成了系列接种,22%(RV5)和 15%(RV1)未完成全剂量接种(p<0.0001)。在治疗该计划内≥10 名患者的 2086 名医生中,78%的医生有超过 50%的患者完成了接种,22%的医生有超过 90%的患者完成了接种。

结论

尽管有两种有效的轮状病毒疫苗和国家免疫建议,但轮状病毒疫苗接种在婴儿中的使用率仍然较低。