Cunnane S C, Armstrong J K
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Canada.
J Nutr. 1990 Apr;120(4):338-45. doi: 10.1093/jn/120.4.338.
The change in long-chain fatty acid composition in maternal liver was studied during pregnancy and lactation in the rat. Maternal liver triglycerides and phospholipids transiently accumulated and were depleted of long-chain fatty acids during pregnancy and lactation. During pregnancy, maternal liver accumulated triglyceride, but triglyceride fatty acid composition changed little. However, maternal liver total phospholipid fatty acid composition changed significantly without a change in the total pool size throughout pregnancy or lactation. The change in composition of (n-3) and (n-6) essential fatty acids in maternal liver triglyceride and total phospholipid occurred in an apparently dyssynchronous manner throughout pregnancy and lactation.
研究了大鼠孕期和哺乳期母体肝脏中长链脂肪酸组成的变化。孕期和哺乳期，母体肝脏中的甘油三酯和磷脂会短暂积累，长链脂肪酸减少。孕期，母体肝脏积累甘油三酯，但甘油三酯脂肪酸组成变化不大。然而，整个孕期或哺乳期，母体肝脏总磷脂脂肪酸组成发生显著变化，而总量不变。孕期和哺乳期，母体肝脏甘油三酯和总磷脂中（n-3）和（n-6）必需脂肪酸的组成变化明显不同步。
