Petukhov E B, Filimonov M I, Aleksandrova N P, Korneev A A
Khirurgiia (Mosk). 1990 Jan(1):27-30.
Changes in the activity of lipid peroxidation (LPO) and the attendant disorders of the properties of the red cells were studied from the results of examination of 32 patients with obstructive jaundice. The data obtained showed that the LPO processes were markedly activated, which led to changes of the red cell membrane properties--reduction of their electric charge, osmotic resistance, and deformity. All this led to metabolic shifts promoting cell destruction. The efficacy of hemosorption was due to sorption of the LPO toxic products rather than to the removal of bilirubin.
通过对32例梗阻性黄疸患者的检查结果，研究了脂质过氧化（LPO）活性的变化以及随之而来的红细胞特性紊乱。所获得的数据表明，LPO过程明显被激活，这导致红细胞膜特性发生变化——其电荷、渗透压抵抗力和变形性降低。所有这些都导致了促进细胞破坏的代谢变化。血液吸附的效果归因于对LPO有毒产物的吸附，而非胆红素的清除。
