Institute of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, and Division of general psychiatry, Nordland hospital, Bodø, Norway.
BMC Psychiatry. 2013 Jan 8;13:13. doi: 10.1186/1471-244X-13-13.
This study will explore the validity of psychiatric diagnoses in administrative registers with special emphasis on comorbid anxiety and substance use disorders.
All new patients admitted to psychiatric hospital in northern Norway during one year were asked to participate. Of 477 patients found eligible, 272 gave their informed consent. 250 patients (52%) with hospital diagnoses comprised the study sample. Expert diagnoses were given on the basis of a structured diagnostic interview (M.I.N.I.PLUS) together with retrospective checking of the records. The hospital diagnoses were blind to the expert. The agreement between the expert's and the clinicians' diagnoses was estimated using Cohen's kappa statistics.
The expert gave a mean of 3.4 diagnoses per patient, the clinicians gave 1.4. The agreement ranged from poor to good (schizophrenia). For anxiety disorders (F40-41) the agreement is poor (kappa = 0.12). While the expert gave an anxiety disorder diagnosis to 122 patients, the clinicians only gave it to 17. The agreement is fair concerning substance use disorders (F10-19) (kappa = 0.27). Only two out of 76 patients with concurrent anxiety and substance use disorders were identified by the clinicians.
The validity of administrative registers in psychiatry seems dubious for research purposes and even for administrative and clinical purposes. The diagnostic process in the clinic should be more structured and treatment guidelines should include comorbidity.
本研究将特别关注合并焦虑和物质使用障碍的情况,探讨行政登记系统中精神科诊断的有效性。
在挪威北部的一家精神病院,我们邀请了所有在一年内入院的新患者参与研究。在符合条件的 477 名患者中,有 272 名患者表示同意。我们将 250 名(52%)有医院诊断的患者纳入研究样本。专家诊断基于结构化诊断访谈(MINI-PLUS)和对记录的回顾性检查。医院诊断对专家是盲态的。我们使用 Cohen's kappa 统计量来评估专家和临床医生诊断之间的一致性。
专家平均为每位患者诊断出 3.4 种疾病,而临床医生平均诊断出 1.4 种。一致性从差到好不等(精神分裂症)。对于焦虑障碍(F40-41),一致性较差(kappa = 0.12)。专家诊断出 122 名患者存在焦虑障碍,而临床医生仅诊断出 17 名。对于物质使用障碍(F10-19),一致性为中等(kappa = 0.27)。临床医生仅识别出 76 名同时存在焦虑和物质使用障碍患者中的 2 名。
行政登记系统在精神科的有效性对于研究目的而言似乎值得怀疑,甚至对于行政和临床目的也是如此。临床诊断过程应更加结构化,治疗指南应包括共病情况。