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亚洲的结直肠癌筛查。

Colorectal cancer screening in Asia.

机构信息

Prince of Wales Hospital, Shatin, NT, Hong Kong, China.

出版信息

Br Med Bull. 2013;105:29-42. doi: 10.1093/bmb/lds040. Epub 2013 Jan 8.

Abstract

INTRODUCTION

The incidence and mortality of colorectal cancer are rapidly rising in several countries in Asia. However, screening guidelines are lacking.

SOURCES OF DATA

Review of literature and local data published in peer review journals.

AREAS OF AGREEMENT

The incidence, anatomical distribution and mortality of colorectal cancer among Asian populations are comparable to those in Western countries. Flat and depressed colonic lesions are not uncommon. Male gender, smoking, obesity, metabolic syndrome and family history are risk factors for colorectal cancer. Certain ethnic groups in Asia have increased susceptibility to colorectal cancer. Faecal occult blood test, flexible sigmoidoscopy and colonoscopy are recommended options for colorectal cancer screening in Asia. Regular screening should start at the age of 50 years.

AREAS OF CONTROVERSY

The optimal screening method in Asia remains unclear. Faecal immunochemical test has been suggested as the first choice of screening test in countries with limited resources. The role of nurse endoscopists in performing endoscopic procedures for colorectal cancer screening in Asia has not been defined.

GROWING POINTS

There is low public awareness and little support by health authorities for screening and prevention of this emerging disease.

AREAS TIMELY FOR DEVELOPING RESEARCH

Screening for colorectal cancer should be a national health priority in most Asian countries. Studies on barriers to screening, education of the public and engagement of family physicians are important strategies in promoting colorectal cancer screening. With more health-care support, increased public acceptance and better access to the general population, colorectal cancer screening in Asia can be rewarding.

摘要

简介

亚洲多个国家的结直肠癌发病率和死亡率正在迅速上升,但缺乏筛查指南。

数据来源

文献综述和同行评议期刊上发表的本地数据。

共识领域

亚洲人群的结直肠癌发病率、解剖分布和死亡率与西方国家相当。平坦和凹陷的结肠病变并不少见。男性、吸烟、肥胖、代谢综合征和家族史是结直肠癌的危险因素。亚洲的某些族群对结直肠癌的易感性增加。粪便潜血试验、乙状结肠镜检查和结肠镜检查是亚洲结直肠癌筛查的推荐选择。亚洲人群应在 50 岁开始定期进行筛查。

争议领域

亚洲最佳筛查方法仍不明确。在资源有限的国家,粪便免疫化学试验已被建议作为首选筛查试验。亚洲在护士内镜医师在结直肠癌筛查内镜操作中的作用尚未明确。

发展点

公众对此病的认识较低,卫生当局对筛查和预防的支持也较少。

亟待研究的领域

在大多数亚洲国家,结直肠癌筛查应成为国家卫生重点。筛查障碍、公众教育和家庭医生参与等方面的研究是促进结直肠癌筛查的重要策略。随着更多的医疗保健支持、公众接受度的提高以及更广泛地普及到普通人群,亚洲的结直肠癌筛查将取得丰硕成果。

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