West Virginia University Eye Institute, Morgantown, West Virginia 26506-9193, USA.
Ophthalmic Plast Reconstr Surg. 2013 Jan-Feb;29(1):51-6. doi: 10.1097/IOP.0b013e318275b754.
This study compared the general health-related quality of life (HRQOL) and the vision-specific HRQOL in patients following the surgical removal of 1 eye who had good vision in the remaining eye to a group of binocular patients with good vision in OU.
The Medical Outcomes Study Short Form 12 and the National Eye Institute Visual Function Questionnaire HRQOL surveys were administered to 29 patients who had surgical removal of an eye who attended an ocular prosthetics clinic and to 25 binocular persons who accompanied a patient. All subjects in each group had best-corrected visual acuity of 20/40 or better. Overall statistical significance was tested using Cramer's V followed by individual t tests for independent groups for each of the scales on the 2 questionnaires to determine whether the means between the 2 groups differed statistically.
The patient group had a mean age of 50.98 years (range, 19-76 years). The control group had a mean age of 49.46 years (range, 18-76 years). The mean time after loss of vision was 28.03 years (range, 1-71 years), and the mean time from surgical removal of the eye was 23.6 years (range, 0.5-59.5 years). There was an overall significant difference between the 2 groups on the 15 derived subscales of the 2 forms (Cramer's V, p = 0.0025). Three general HRQOL subscales (Short Form 12-mental component summary, Short Form 12 physical component summary, and National Eye Institute Visual Function Questionnaire-General Health) showed no differences between the 2 groups (p = 0.48, p = 0.81, and p = 0.78, respectively). Three of the 12 vision-specific National Eye Institute Visual Function Questionnaire subscales demonstrated statistically significant differences between the patient and control groups: peripheral vision (p = 0.0006), role difficulties (p = 0.015), and the composite score (p = 0.014). In addition, 2 monocular patients had given up driving compared with no binocular subjects (p = 0.056).
This population of monocular patients had general physical and mental HRQOL equivalent to the normal binocular group despite the surgical removal of 1 eye. However, the reduced vision-specific HRQOL of monocular patients on the National Eye Institute Visual Function Questionnaire indicates that there are substantial residual visual deficits even after prolonged monocular status.
本研究比较了因单眼手术切除而保留单眼良好视力的患者与双眼视力良好的患者之间的一般健康相关生活质量（HRQOL）和特定于视力的 HRQOL。
对 29 名在眼假体诊所就诊的单眼手术切除患者和 25 名陪同患者的双眼患者进行了医疗结局研究简表 12 项和国家眼科研究所视觉功能问卷 HRQOL 调查。每组中的所有受试者均有 20/40 或更好的最佳矫正视力。使用 Cramer's V 进行整体统计显着性检验，然后对每个问卷的 2 个量表上的每个量表进行独立组的个体 t 检验，以确定 2 组之间的平均值是否在统计学上存在显着差异。
患者组的平均年龄为 50.98 岁（范围，19-76 岁）。对照组的平均年龄为 49.46 岁（范围，18-76 岁）。失去视力后的平均时间为 28.03 年（范围，1-71 年），从单眼手术切除到平均时间为 23.6 年（范围，0.5-59.5 年）。两组在两种形式的 15 个衍生子量表上存在整体显着差异（Cramer's V，p = 0.0025）。两个一般 HRQOL 子量表（短表 12 心理成分总结，短表 12 身体成分总结和国家眼科研究所视觉功能问卷-一般健康）在两组之间没有差异（p = 0.48，p = 0.81 和 p = 0.78）。12 个国家眼科研究所视觉功能问卷特定于视力的子量表中有 3 个在患者组和对照组之间显示出统计学上的显着差异：周边视力（p = 0.0006），角色困难（p = 0.015）和综合评分（p = 0.014）。此外，与没有双眼的患者相比，2 名单眼患者已经放弃了驾驶（p = 0.056）。
尽管一只眼接受了手术切除，但这组单眼患者的一般身体和精神 HRQOL 与正常双眼组相当。但是，单眼患者的国家眼科研究所视觉功能问卷中视力特定的 HRQOL 降低表明，即使在长时间单眼状态下，仍存在严重的残余视力缺陷。
