Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, Moorenstrasse 5, 40225 Dusseldorf, Germany.
Eur Radiol. 2013 Jun;23(6):1503-9. doi: 10.1007/s00330-012-2750-5. Epub 2013 Jan 9.
Organ-specific dose reduction (OSDR) algorithms can reduce radiation on radiosensitive organs up to 59 %. This study evaluates the influence of a new OSDR algorithm on image quality of head and neck computed tomographic angiography (CTA) in clinical routine.
Sixty-two consecutive patients (68 ± 13 years) were randomised into two groups and imaged using 128-row multidetector CT. Group A (n = 31) underwent conventional CTA and group B (n = 31) CTA with a novel OSDR algorithm. Subjective and objective image quality were statistically compared. Subjective image quality was rated on a five-point scale. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated with region-of-interest measurements.
The SNR of the common carotid artery and middle cerebral artery was 53.6 ± 22.7 and 43.3 ± 15.3 (group A) versus 54.1 ± 20.5 and 46.2 ± 14.6 (group B). The CNR was 40.0 ± 19.3 and 29.7 ± 12.0 (group A) compared with 40.7 ± 16.8 and 32.9 ± 10.9 (group B), respectively. Subjective image quality was excellent in both groups (mean score 4.4 ± 0.7 versus 4.4 ± 0.6). Differences between the two groups were not significant.
The novel OSDR algorithm does not compromise image quality of head and neck CTA. Its application can be recommended for CTA in clinical routine to protect the thyroid gland and ocular lenses from unnecessary high radiation.
• Organ-specific dose reduction (OSDR) can significantly reduce radiation exposure during CT • OSDR does not compromise image quality of head and neck CTA • OSDR can significantly lower the risk of radiation damage to sensitive organs • OSDR can easily be applied in routine clinical practice.
器官特异性剂量降低（OSDR）算法可使辐射敏感器官的剂量降低多达 59%。本研究旨在评估一种新的 OSDR 算法对临床常规头颈部 CT 血管造影（CTA）图像质量的影响。
连续 62 例患者（68±13 岁）分为两组，使用 128 排多层 CT 进行检查。A 组（n=31）行常规 CTA，B 组（n=31）行新型 OSDR 算法 CTA。对两组的主观和客观图像质量进行统计学比较。主观图像质量评分采用五分制。采用感兴趣区测量计算信噪比（SNR）和对比噪声比（CNR）。
颈总动脉和大脑中动脉的 SNR 分别为 53.6±22.7 和 43.3±15.3（A 组）与 54.1±20.5 和 46.2±14.6（B 组）。CNR 分别为 40.0±19.3 和 29.7±12.0（A 组）与 40.7±16.8 和 32.9±10.9（B 组）。两组的主观图像质量均为优秀（平均评分为 4.4±0.7 与 4.4±0.6）。两组间差异无统计学意义。
新型 OSDR 算法不会降低头颈部 CTA 的图像质量。该算法可应用于临床常规 CTA 中，以保护甲状腺和眼晶体免受不必要的高剂量辐射。
器官特异性剂量降低（OSDR）可显著降低 CT 检查的辐射暴露量。
OSDR 不会降低头颈部 CTA 的图像质量。
OSDR 可显著降低敏感器官的辐射损伤风险。
OSDR 可轻松应用于临床常规实践。
