Okeke T C, Obi S N, Okezie O A, Ugwu E O V, Akogu S P O, Ocheni S, Ezenyeaku C C T
Department Of Obstetrics And Gynaccology, University of Nigeria Teaching Hospital, Enugu.
Niger J Med. 2012 Jan-Mar;21(1):57-60.
Hepatitis B and C viruses coinfection in HIV positive pregnant women is a common public health problem and recognized worldwide. The consequences of this problem in our poor resource setting with the risk of mother to child transmission is obvious with increased morbidity and mortality in our environment.
To determine the prevalence of coinfection patterns of HBV and HCV among HIV positive pregnant women in Enugu Nigeria.
A retrospective survey conducted on 401 Nigeria HIV positive pregnant women seen at Prevention of Mother To Child Transmission (PMTCT) clinic at the UNTH Enugu Nigeria over a 3 year period between 1st January 2007 and 31st December 2009.
The prevalence of hepatitis B and C viruses coinfection among HIV positive pregnant women in Enugu is 6.5%. HIV/HBV coinfection was commoner than HIV/HCV coinfection. There was no significant association between hepatitis B and C viruses coinfection and the age, ethnic group, marital or educational status of the women (P > 0.05).
There is high prevalence of hepatitis B and C coinfection among HIV positive pregnant women in Enugu. This high burden of these hepatotropie virus coinfection calls for continued need to screen for these infections and vaccinate the affected babies for hepatitis B and/or C where appropriate.
艾滋病毒阳性孕妇中的乙型肝炎病毒和丙型肝炎病毒合并感染是一个常见的公共卫生问题，在全球范围内都得到了认可。在我们资源匮乏的环境中，这个问题导致母婴传播风险增加，其后果在我们的环境中表现为发病率和死亡率上升，这是显而易见的。
确定尼日利亚埃努古艾滋病毒阳性孕妇中乙肝病毒和丙肝病毒合并感染模式的患病率。
对2007年1月1日至2009年12月31日期间在尼日利亚埃努古联合国教学医院母婴传播预防（PMTCT）诊所就诊的401名尼日利亚艾滋病毒阳性孕妇进行了回顾性调查。
埃努古艾滋病毒阳性孕妇中乙型肝炎病毒和丙型肝炎病毒合并感染的患病率为6.5%。艾滋病毒/乙肝病毒合并感染比艾滋病毒/丙肝病毒合并感染更为常见。乙肝病毒和丙肝病毒合并感染与这些女性的年龄、种族、婚姻或教育状况之间没有显著关联（P>0.05）。
埃努古艾滋病毒阳性孕妇中乙肝和丙肝合并感染的患病率很高。这些嗜肝病毒合并感染的高负担表明，持续需要对这些感染进行筛查，并在适当情况下为受影响的婴儿接种乙肝和/或丙肝疫苗。
