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纳米材料的毒性与细胞死亡方式。

Nanomaterials toxicity and cell death modalities.

作者信息

De Stefano Daniela, Carnuccio Rosa, Maiuri Maria Chiara

机构信息

Dipartimento di Farmacologia Sperimentale, Facoltà di Scienze Biotecnologiche, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80139 Napoli, Italy.

出版信息

J Drug Deliv. 2012;2012:167896. doi: 10.1155/2012/167896. Epub 2012 Dec 5.

DOI:10.1155/2012/167896
PMID:23304518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3523142/
Abstract

In the last decade, the nanotechnology advancement has developed a plethora of novel and intriguing nanomaterial application in many sectors, including research and medicine. However, many risks have been highlighted in their use, particularly related to their unexpected toxicity in vitro and in vivo experimental models. This paper proposes an overview concerning the cell death modalities induced by the major nanomaterials.

摘要

在过去十年中，纳米技术的进步在包括研究和医学在内的许多领域开发了大量新颖且引人入胜的纳米材料应用。然而，它们的使用中已凸显出许多风险，特别是与其在体外和体内实验模型中意想不到的毒性有关。本文概述了主要纳米材料诱导的细胞死亡方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/d15485673bd7/JDD2012-167896.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/fa42796de8cf/JDD2012-167896.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/0621720bdc87/JDD2012-167896.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/7c4d741e7f29/JDD2012-167896.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/d15485673bd7/JDD2012-167896.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/fa42796de8cf/JDD2012-167896.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/0621720bdc87/JDD2012-167896.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/7c4d741e7f29/JDD2012-167896.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f8d/3523142/d15485673bd7/JDD2012-167896.004.jpg

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