Hayes David A, Miller Larry E, Block Jon E
Brisbane Orthopedic and Sports Medicine Center, Level 5, 259 Wickham Terrace, Brisbane, QLD 4000, Australia.
Case Rep Orthop. 2012;2012:297326. doi: 10.1155/2012/297326. Epub 2012 Dec 6.
Osteoarthritis (OA) is a leading cause of disability in middle-aged and older adults with the prevalence expected to increase by 40% by 2025. This dramatic projected increase in OA reflects, in large part, the alarming obesity epidemic. Indeed, it is now well understood that abnormal loading across the knee joint due to malalignment and/or excessive weight gain is responsible for accelerating OA progression. Consequently, there is a therapeutic need for alternative knee OA treatments that directly address joint overload to fill the gap between ineffective conservative care and invasive joint-modifying surgical procedures. We describe two cases that presented with bilateral knee OA resistant to conservative treatments, each with one knee previously and unsuccessfully treated with high tibial osteotomy to improve alignment and the contralateral knee successfully treated with a joint-preserving, load-absorbing implant (KineSpring Knee Implant System).
骨关节炎(OA)是中老年人残疾的主要原因,预计到2025年其患病率将增加40%。OA这种显著的预计增长在很大程度上反映了令人担忧的肥胖流行趋势。事实上,现在人们已经清楚地认识到,由于关节排列不齐和/或体重过度增加导致的膝关节异常负荷是加速OA进展的原因。因此,迫切需要直接解决关节过载问题的替代性膝骨关节炎治疗方法,以填补无效保守治疗与侵入性关节改良手术之间的空白。我们描述了两例双侧膝骨关节炎患者,他们对保守治疗均有抵抗,其中一例患者的一侧膝关节曾接受高位胫骨截骨术以改善关节排列,但未成功,而另一侧膝关节则成功接受了保留关节、吸收负荷的植入物(KineSpring膝关节植入系统)治疗。