Clifford A, O'Connell M, Gabriel S, Miller L E, Block J E
Moximed, Inc., 26460 Corporate Avenue, Hayward, CA 94545, USA.
J Med Eng Technol. 2011 Jan;35(1):65-71. doi: 10.3109/03091902.2010.535592.
Osteoarthritis (OA) of the knee is the leading cause of disability in the adult population. Although a number of treatments for knee OA are available, none effectively prevent OA progression. Currently, a wide therapeutic gap exists for patients who have unsuccessfully exhausted conservative OA treatments but who are hesitant or ineligible to undergo invasive surgery. The KineSpring device is a novel, joint preserving, minimally invasive implant that reduces medial compartment loading without significantly impacting the loading of the lateral compartment. This article describes the rationale for and the design of the KineSpring device and summarizes results of initial biomechanical testing in an OA cadaver model.
膝关节骨关节炎(OA)是成年人群致残的主要原因。尽管有多种治疗膝关节OA的方法,但没有一种能有效阻止OA的进展。目前,对于那些保守治疗OA失败但又犹豫是否接受或不适合接受侵入性手术的患者,存在很大的治疗差距。KineSpring装置是一种新型的、保留关节的微创植入物,可减少内侧间室负荷,而不会显著影响外侧间室的负荷。本文介绍了KineSpring装置的原理和设计,并总结了在OA尸体模型中进行的初步生物力学测试结果。