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酗酒者对双硫仑的态度及经历

Alcoholics' attitudes toward and experiences with disulfiram.

作者信息

Liskow B, Nickel E, Tunley N, Powell B J, Penick E C

机构信息

Kansas City VAMC, Missouri 64128.

出版信息

Am J Drug Alcohol Abuse. 1990;16(1-2):147-60. doi: 10.3109/00952999009001579.

DOI:10.3109/00952999009001579
PMID:2330935
Abstract

We studied 345 alcoholic inpatients utilizing a 43-item questionnaire designed to assess these patients' attitudes toward and experiences with disulfiram. A surprisingly high number of patients who had received disulfiram drank ethanol while taking or within 1 week of stopping disulfiram and experienced a disulfiram ethanol reaction. This finding and others derived from the questionnaire are reported, and the potential implications of the findings are discussed.

摘要

我们使用一份包含43个条目的问卷对345名酒精中毒住院患者进行了研究,该问卷旨在评估这些患者对双硫仑的态度及使用双硫仑的经历。在接受双硫仑治疗的患者中,有相当多的人在服用双硫仑期间或停药后1周内饮用了乙醇,并出现了双硫仑-乙醇反应。本文报告了这一发现以及从问卷中得出的其他结果,并讨论了这些结果可能产生的影响。

相似文献

1
Alcoholics' attitudes toward and experiences with disulfiram.酗酒者对双硫仑的态度及经历
Am J Drug Alcohol Abuse. 1990;16(1-2):147-60. doi: 10.3109/00952999009001579.
2
Giving ethanol to alcoholics in a research setting: its effect on compliance with disulfiram treatment.
Br J Addict. 1990 Jan;85(1):119-23. doi: 10.1111/j.1360-0443.1990.tb00630.x.
3
A one-year follow-up of men alcoholics given disulfiram.对接受双硫仑治疗的男性酗酒者进行的为期一年的随访。
J Stud Alcohol. 1985 May;46(3):191-5. doi: 10.15288/jsa.1985.46.191.
4
Disulfiram treatment of alcoholism. A Veterans Administration cooperative study.戒酒硫治疗酒精中毒。一项退伍军人管理局合作研究。
JAMA. 1986 Sep 19;256(11):1449-55.
5
Alcoholism treatment by disulfiram and community reinforcement therapy.
J Behav Ther Exp Psychiatry. 1982 Jun;13(2):105-12. doi: 10.1016/0005-7916(82)90050-7.
6
Behavioral use of disulfiram in the treatment of problem drinking.双硫仑在问题饮酒治疗中的行为学应用。
Int J Addict. 1987 May;22(5):445-54. doi: 10.3109/10826088709027440.
7
Disulfiram implantation. A placebo-controlled trial with two-year follow-up.双硫仑植入。一项为期两年随访的安慰剂对照试验。
J Stud Alcohol. 1978 May;39(5):809-19. doi: 10.15288/jsa.1978.39.809.
8
Difficulties of disulfiram therapy with alcoholics.戒酒硫对酗酒者治疗的困难。
Q J Stud Alcohol. 1971 Mar;32(1):168-71.
9
Alcoholic patients' experience and attitudes on pharmacotherapy for alcoholism.
J Addict Dis. 1998;17(3):35-47. doi: 10.1300/J069v17n03_04.
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[Disulfiram in outpatient treatment of alcohol dependency].[双硫仑用于酒精依赖的门诊治疗]
Nervenarzt. 2016 May;87(5):506-12. doi: 10.1007/s00115-015-4339-0.

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Alcohol Clin Exp Res (Hoboken). 2025 Apr;49(4):725-735. doi: 10.1111/acer.70022. Epub 2025 Mar 11.
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Is the concept of compulsion useful in the explanation or description of addictive behaviour and experience?强迫观念这一概念在解释或描述成瘾行为及体验方面是否有用?
Addict Behav Rep. 2017 May 18;6:15-38. doi: 10.1016/j.abrep.2017.05.002. eCollection 2017 Dec.
3
Adverse effects of disulfiram and patient compliance.
双硫仑的不良反应与患者依从性。
Indian J Psychiatry. 1996 Jan;38(1):47-50.
4
Status of disulfiram in present day alcoholic deaddiction therapy.双硫仑在当今酒精戒毒治疗中的地位。
Indian J Psychiatry. 2011 Jan;53(1):25-9. doi: 10.4103/0019-5545.75557.
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Delirium-associated disulfiram and ethanol interactions.谵妄相关的双硫仑与乙醇相互作用。
Prim Care Companion J Clin Psychiatry. 2005;7(5):235-7. doi: 10.4088/pcc.v07n0505.
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Pharmacokinetic and pharmacodynamic principles of illicit drug use and treatment of illicit drug users.非法药物使用的药代动力学和药效学原理以及非法药物使用者的治疗
Clin Pharmacokinet. 1997 Nov;33(5):344-400. doi: 10.2165/00003088-199733050-00003.