Cole Eye Institute, Cleveland Clinic Foundation, Refractive Surgery Department, Cleveland, OH, USA.
J Refract Surg. 2013 Jan;29(1):42-8. doi: 10.3928/1081597X-20121210-03.
To analyze the induced corneal higher order aberrations (HOAs) after wavefront-optimized ablation.
Sixty-four myopic eyes that underwent wavefront-optimized myopic LASIK were divided into three groups based on spherical equivalent (SE): low myopia group (23 eyes with SE <-3.00 diopters [D]); moderate myopia group (27 eyes with SE between -3.00 and -6.00 D); and high myopia group (14 eyes with SE >-6.00 D). Total corneal HOA, corneal spherical aberrations, corneal coma through a 6-mm pupil size, and corneal eccentricity were measured with a dual Scheimpflug imaging device preoperatively and 3 months after surgery.
An overall increase in total corneal HOA was observed with a mean of 0.18±0.18 μm (P<.01), although this induction was not statistically significant in the low myopic group with a mean of 0.006±0.15 μm (P=.85). Root-mean-square spherical aberration varied the most after myopic ablation, with an overall induction of positive spherical aberration of 0.27±0.25 μm (P<.001).
Although the wavefront-optimized profile was designed to preserve the preoperative HOAs of the total eye, a significant induction of the corneal HOAs after myopic treatment was observed. The magnitude of the induced corneal HOA was related to the amount of intended correction. Corneal wavefront profiles do not reflect the visual performance; however, they provide relevant information, which may help in optimizing new laser treatment algorithms.
分析波前优化消融术后诱导的角膜高阶像差(HOAs)。
根据等效球镜度(SE)将 64 只接受波前优化的近视 LASIK 手术的近视眼分为三组:低度近视组(23 只 SE<-3.00 屈光度[D]);中度近视组(27 只 SE 在-3.00 至-6.00 D 之间);高度近视组(14 只 SE>-6.00 D)。术前和术后 3 个月,使用双 Scheimpflug 成像设备测量总角膜 HOAs、角膜球差、6mm 瞳孔大小的角膜彗差和角膜偏心度。
总角膜 HOAs 总体增加,平均增加 0.18±0.18μm(P<.01),尽管在 SE 平均为 0.006±0.15μm(P=.85)的低度近视组中,这种诱导没有统计学意义。在近视消融术后,根均方球差变化最大,总体诱导正性球差 0.27±0.25μm(P<.001)。
尽管波前优化的形态旨在保留总眼的术前 HOAs,但在近视治疗后观察到角膜 HOAs 有明显的诱导。诱导的角膜 HOAs 的大小与预期矫正量有关。角膜波前形态并不能反映视觉性能,但它们提供了相关信息,这可能有助于优化新的激光治疗算法。