Department of Orthopaedics, Centre for Hip Health and Mobility, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Rheum Dis Clin North Am. 2013 Feb;39(1):21-44. doi: 10.1016/j.rdc.2012.11.002.
Mechanics play a role in the initiation and progression of osteoarthritis. However, our understanding of which mechanical parameters are most important, and what their impact is on the disease, is limited by the challenge of measuring the most important mechanical quantities in living subjects. Consequently, comprehensive statements cannot be made about how mechanics should be modified to prevent, slow or arrest osteoarthritis. Our current understanding is based largely on studies of deviations from normal mechanics caused by malalignment, injury, and deformity. Some treatments for osteoarthritis focus on correcting mechanics, but there appears to be scope for more mechanically based interventions.
力学在骨关节炎的发生和发展中起着一定的作用。然而，由于难以测量活体中最重要的力学参数，我们对于哪些力学参数最重要以及它们对疾病的影响的认识受到了限制。因此，对于如何改变力学以预防、减缓或阻止骨关节炎，我们尚不能做出全面的陈述。目前的认识主要基于对因对线不良、损伤和畸形引起的正常力学偏离的研究。一些骨关节炎的治疗方法侧重于纠正力学，但似乎有更多基于力学的干预措施的空间。
