Lobo Ronstan, Fraser Alexander, Kiely Patrick, Boers Peter
Department of Medicine, University Hospital Limerick, Dooradoyle, Limerick, Ireland.
BMJ Case Rep. 2013 Jan 10;2013:bcr2012008057. doi: 10.1136/bcr-2012-008057.
This case describes a woman with a history of rheumatoid arthritis with secondary vasculitic skin ulcers, Sicca syndrome and idiopathic Parkinson's disease that was diagnosed by a neurologist in 2005. The patient's parkinsonian symptoms were difficult to control, despite the use of antiparkinsonian medications. During a regular clinical review in 2011, the patient's rheumatologist had prescribed cyclophosphamide infusions to help with the vasculitic skin ulcers. Over the following 2 months, the patient's parkinsonian symptoms completely resolved.
该病例描述了一名患有类风湿性关节炎并伴有继发性血管炎性皮肤溃疡、干燥综合征和特发性帕金森病的女性,其帕金森病于2005年由一名神经科医生确诊。尽管使用了抗帕金森药物,但患者的帕金森症状仍难以控制。在2011年的一次常规临床检查中,患者的风湿病医生开了环磷酰胺静脉输注治疗,以帮助治疗血管炎性皮肤溃疡。在接下来的两个月里,患者的帕金森症状完全消失了。