School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P R China.
ACS Comb Sci. 2013 Feb 11;15(2):130-4. doi: 10.1021/co300139s. Epub 2013 Jan 31.
A facile and efficient method has been developed for the synthesis of a small library of dibenzo[b,f][1,4]thiazepin-11(10H)-ones via Smiles rearrangement. Compounds were obtained in excellent isolated yields (70%-92%) under metal-free conditions. More specifically, this transition metal-free process relates to an environmentally friendly, economical, and efficient method for preparing benzoic-fused seven-membered lactams.
已经开发出一种简便有效的方法，通过 Smiles 重排来合成一小部分二苯并[b,f][1,4]噻嗪-11(10H)-酮。在无金属条件下，化合物以优异的分离收率（70%-92%）获得。更具体地说，这种无过渡金属的过程涉及一种环境友好、经济高效的方法，用于制备苯并稠合的七元内酰胺。
