Ning Yuming, McAvay Gail, Chaudhry Sarwat I, Arnold Alice M, Allore Heather G
Section of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06511, USA.
Exp Aging Res. 2013;39(1):27-43. doi: 10.1080/0361073X.2013.741968.
BACKGROUND/STUDY CONTEXT: The objective of this study was to examine sequential and simultaneous approaches to multiple imputation of missing data in a longitudinal data set where losses due to death were common.
Comparison of results from analyses and simulations of time to incident difficulty of activities of daily living (ADL) in the Cardiovascular Health Study when missing data were imputed simultaneously or sequentially.
Results differed with imputation methods. The largest proportional differences in 12 risk factor parameter estimates were heart failure by 106%, social support by 33%, and arthritis by 27%.
Decedents' final characteristics were influential on future imputations of those with missing values.
背景/研究背景:本研究的目的是检验在纵向数据集中对缺失数据进行多次插补的顺序法和同步法,在该数据集中因死亡导致的数据缺失很常见。
在心血管健康研究中,当对缺失数据进行同步或顺序插补时,比较分析结果和对日常生活活动(ADL)发生困难时间的模拟结果。
插补方法不同,结果也不同。12个风险因素参数估计值的最大比例差异为心力衰竭106%、社会支持33%、关节炎27%。
死者的最终特征对缺失值者未来的插补有影响。