UMR 930 Imagerie et Cerveau, Inserm, Université François Rabelais de Tours, CHRU de Tours, France.
Psychophysiology. 2013 Mar;50(3):240-52. doi: 10.1111/psyp.12006. Epub 2013 Jan 14.
Children with Autism Spectrum Disorder (ASD) may display atypical behaviors in reaction to unattended changes that occur in all sensory modalities. Atypical automatic auditory change processing has been highlighted in ASD via the analysis of mismatch negativity (MMN). The present study investigated visual deviancy detection in children with ASD in order to determine whether unusual reactions to change operate in other sensory modalities. Twelve children with ASD were presented with a passive visual oddball paradigm using dynamic stimuli. Compared to controls, children with ASD showed an earlier visual mismatch response, suggesting a hypersensitivity to visual deviancy. This study is thus consistent with the hypothesis of the existence of "general" atypical change detection processing in children with ASD that might contribute to their intolerance of change.
自闭症谱系障碍（ASD）儿童在对所有感觉模式中发生的无人关注的变化做出反应时可能会表现出异常行为。通过对失匹配负波（MMN）的分析，已经在 ASD 中强调了异常的自动听觉变化处理。本研究通过使用动态刺激的被动视觉偏离范式，调查了 ASD 儿童的视觉偏差检测，以确定对变化的异常反应是否在其他感觉模式中起作用。与对照组相比，患有 ASD 的儿童表现出更早的视觉失匹配反应，这表明他们对视觉偏差过度敏感。因此，这项研究与 ASD 儿童存在“普遍”异常变化检测处理的假设一致，这可能导致他们对变化的不耐受。
