Shayanfar Nasrin, Babaheidarian Pegah, Rahmani Hoda, Azadmanesh Keyhan, Sohrabi Amir, Mohammadpour Masoud, Mirzaie Ali Zare, Parvaneh Nima
Department of Pathology, Hazrat-e-Rasoul Hospital, Teheran University of Medical Sciences, Iran.
Acta Dermatovenerol Croat. 2012;20(4):267-71.
Epidermodysplasia verruciformis is a rare genodermatosis characterized by inherited susceptibility to infection with certain papillomaviruses, which leads to the development of disseminated plane wart-like lesions. In some patients, lesions resembling pityriasis versicolor appear. Epidermodysplasia verruciformis has also been reported in immunosuppressed patients, most notably those with HIV infection. The affected patients are predisposed to development of skin and mucosal malignancies. We describe the rare occurrence of plasmablastic lymphoma in a patient with long lasting epidermodysplasia verruciformis and hepatitis B virus infection.
疣状表皮发育不良是一种罕见的遗传性皮肤病,其特征是对某些乳头瘤病毒感染具有遗传易感性,这会导致播散性扁平疣样病变的发展。在一些患者中,会出现类似花斑癣的病变。疣状表皮发育不良在免疫抑制患者中也有报道,最显著的是那些感染HIV的患者。受影响的患者易患皮肤和黏膜恶性肿瘤。我们描述了一名患有长期疣状表皮发育不良和乙型肝炎病毒感染的患者罕见地发生了浆母细胞淋巴瘤。