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[吸烟习惯与阻塞性睡眠呼吸暂停低通气综合征的严重程度]

[Smoking habits and severity of obstructive sleep apnea hypopnea syndrome].

作者信息

Boussoffara L, Boudawara N, Sakka M, Knani J

机构信息

Service de pneumologie, hôpital Tahar Sfar de Mahdia, 5100 Mahdia, Tunisie.

出版信息

Rev Mal Respir. 2013 Jan;30(1):38-43. doi: 10.1016/j.rmr.2012.08.009. Epub 2012 Nov 13.

Abstract

INTRODUCTION

Smoking habits have many adverse health effects. The effect of tobacco on obstructive sleep apnea hypopnea syndrome is well-documented but the effect on the severity of this syndrome has not been completely established.

AIM OF THIS STUDY

Evaluate the effect of tobacco on the severity of sleep apnea hypopnea syndrome.

PATIENTS AND METHODS

During 4 years 307, patients were referred to our department for a suspicion of obstructive sleep apnea hypopnea syndrome. Among these patients, only 151 patients had an obstructive sleep apnea syndrome confirmed by nocturnal polygraph. Smoking status, clinical and spirometric data were determined in these 151 patients.

RESULTS

Among these 151 patients, 101 were non-smokers and 50 current smokers. The apnea and hypopnea index (AHI) were higher among current smokers than non-smokers (42.96/h versus 28.77/h; P<0.0001). The percent of patients who had a not severe obstructive sleep apnea syndrome were higher among non-smokers than current smokers patients (P=0.009). Current smokers were 3.7 times more likely having severe obstructive sleep apnea hypopnea syndrome than non-smokers (OR=3.7; P=0.001).

CONCLUSION

Smoking habits seems to be associated with the severity of obstructive sleep apnea syndrome that's why smoking cessation is very important in the treatment of obstructive sleep apnea hypopnea syndrome.

摘要

引言

吸烟习惯对健康有许多不利影响。烟草对阻塞性睡眠呼吸暂停低通气综合征的影响已有充分记录,但对该综合征严重程度的影响尚未完全明确。

本研究目的

评估烟草对睡眠呼吸暂停低通气综合征严重程度的影响。

患者与方法

在4年期间,有307名患者因疑似阻塞性睡眠呼吸暂停低通气综合征转诊至我科。在这些患者中,只有151名患者通过夜间多导睡眠监测仪确诊为阻塞性睡眠呼吸暂停综合征。对这151名患者确定了吸烟状况、临床和肺功能数据。

结果

在这151名患者中,101名是非吸烟者,50名是当前吸烟者。当前吸烟者的呼吸暂停低通气指数(AHI)高于非吸烟者(42.96次/小时对28.77次/小时;P<0.0001)。非吸烟者中患有非重度阻塞性睡眠呼吸暂停综合征的患者百分比高于当前吸烟者(P=0.009)。当前吸烟者患重度阻塞性睡眠呼吸暂停低通气综合征的可能性是非吸烟者的3.7倍(比值比=3.7;P=0.001)。

结论

吸烟习惯似乎与阻塞性睡眠呼吸暂停综合征的严重程度相关,这就是为什么戒烟在阻塞性睡眠呼吸暂停低通气综合征的治疗中非常重要。

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