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不同动物物种中超氧化物歧化酶的比较研究。

A comparative study of superoxide dismutase in various animal species.

作者信息

Izokun-Etiobhio B O, Oraedu A C, Ugochukwu E N

机构信息

Department of Biochemistry, University of Benin, Nigeria.

出版信息

Comp Biochem Physiol B. 1990;95(3):521-3. doi: 10.1016/0305-0491(90)90013-j.

DOI:10.1016/0305-0491(90)90013-j
PMID:2331878
Abstract
  1. Superoxide dismutase activity has been determined in liver homogenates of five species. There were no significant differences in the activities of the enzyme in the rat, rainbow lizard, wall gecko and chicken. The activity was significantly lower in the fish. 2. The order of activity of the enzyme in the organs/tissues of the rat was liver greater than kidney greater than heart greater than skeletal muscle greater than brain greater than lung greater than spleen greater than spinal cord greater than retina greater than pancrease greater than lens greater than small intestine. 3. Inhibition studies with cyanide showed that the enzyme in the liver of the various animal species was inhibited by cyanide. 4. The developmental pattern for the enzyme showed no significant changes in the liver of the rat from birth and up to 7 weeks after. However, the activity increased at about 8 weeks and remained constant to adult life.
摘要
  1. 已测定了五个物种肝脏匀浆中的超氧化物歧化酶活性。大鼠、彩虹蜥蜴、壁虎和鸡体内该酶的活性没有显著差异。鱼类体内该酶的活性显著较低。2. 大鼠各器官/组织中该酶的活性顺序为:肝脏>肾脏>心脏>骨骼肌>大脑>肺>脾脏>脊髓>视网膜>胰腺>晶状体>小肠。3. 用氰化物进行的抑制研究表明,各种动物肝脏中的该酶都能被氰化物抑制。4. 该酶的发育模式显示,大鼠出生后直至7周龄,其肝脏中的该酶没有显著变化。然而,该酶活性在约8周龄时增加,并在成年期保持稳定。

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A comparative study of superoxide dismutase in various animal species.不同动物物种中超氧化物歧化酶的比较研究。
Comp Biochem Physiol B. 1990;95(3):521-3. doi: 10.1016/0305-0491(90)90013-j.
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[Superoxide dismutase and catalase in organs of mammalians with various ecological genesis].[不同生态起源哺乳动物器官中的超氧化物歧化酶和过氧化氢酶]
Zh Evol Biokhim Fiziol. 2001 May-Jun;37(3):183-6.
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Isolation and characterization of basic superoxide dismutase consisting of Mr-25,000 subunits in rat liver.大鼠肝脏中由Mr-25,000亚基组成的碱性超氧化物歧化酶的分离与特性分析。
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Superoxide dismutase in the rat and mouse as a function of age and longevity.大鼠和小鼠体内超氧化物歧化酶与年龄和寿命的关系。
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Superoxide dismutase provides protection against the hyperoxia in the retina of the rainbow trout (Salmo gairdneri).超氧化物歧化酶为虹鳟(Salmo gairdneri)视网膜中的高氧环境提供保护。
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Comparison of cytoplasmic superoxide dismutase in liver, heart and brain of aging rats and mice.衰老大鼠和小鼠肝脏、心脏及大脑中细胞质超氧化物歧化酶的比较。
Biochem Biophys Res Commun. 1976 Nov 22;73(2):255-62. doi: 10.1016/0006-291x(76)90701-4.
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Evaluation of negative staining technique for determination of CN--insensitive superoxide dismutase activity.用于测定对氰化物不敏感的超氧化物歧化酶活性的负染色技术评估。
Biochim Biophys Acta. 1979 Jan 12;566(1):32-9. doi: 10.1016/0005-2744(79)90245-6.