University of Minnesota, Minneapolis, MN 554555, USA.
Biol Psychol. 2013 Apr;93(1):122-31. doi: 10.1016/j.biopsycho.2013.01.001. Epub 2013 Jan 11.
Previous research has found that individuals with obsessive-compulsive (OC) symptoms show larger error-related negativity (ERN) and correct-response negativity (CRN) amplitudes than controls. Task difficulty was manipulated during a flanker task and a probabilistic learning task to determine the effect of difficulty on ERN and CRN amplitudes in those with high or low levels of OC symptoms. Increasing task difficulty during a flanker task attenuated ERN amplitudes and enhanced CRN amplitudes. Although larger ERN amplitudes were found in the high OC group compared to the low OC group during the easy flanker task, this group difference was no longer apparent during the difficult version of the flanker task. Increasing difficulty during the probabilistic learning task had no effect on group differences in ERN or CRN amplitudes. The results of this study suggest that the hyperactive error-monitoring activity associated with OC symptoms depends on the difficulty and type of task performed.
先前的研究发现，与对照组相比，具有强迫观念-强迫行为（OC）症状的个体表现出更大的错误相关负性波（ERN）和正确反应负性波（CRN）幅度。在侧抑制任务和概率学习任务中操纵任务难度，以确定在 OC 症状水平较高或较低的个体中，难度对 ERN 和 CRN 幅度的影响。在侧抑制任务中增加任务难度会减弱 ERN 幅度并增强 CRN 幅度。尽管在简单的侧抑制任务中，高 OC 组的 ERN 幅度比低 OC 组大，但在困难版本的侧抑制任务中，这种组间差异不再明显。在概率学习任务中增加难度对 ERN 或 CRN 幅度的组间差异没有影响。这项研究的结果表明，与 OC 症状相关的过度活跃的错误监测活动取决于所执行任务的难度和类型。
