Baydur A, Swank S M, Stiles C M, Sassoon C S
Department of Internal Medicine, University of Southern California, Downey.
Chest. 1990 May;97(5):1157-64. doi: 10.1378/chest.97.5.1157.
To our knowledge, the effects of corrective spinal surgery on total respiratory mechanics and its components in anesthetized patients with kyphoscoliosis have not been previously reported in detail. We studied 13 patients with kyposcoliosis; their mean (+/- SD) age was 24.7 +/- 2.1 years; eight underwent anterior and posterior spinal fusions (AF and PF, respectively) two weeks apart (group A), four underwent PF alone (group B), and one had a three-stage procedure. Mean total respiratory elastance (Ers), static and dynamic lung elastance (Est,L and Edyn,L, respectively), chest wall elastance (Ew), and lung resistance (RL) were derived according to previously described methodology. In group A, Ers and Ew increased by 39 percent and 58 percent, respectively, following AF and by 20 percent and 129 percent following PF, while Est,L and Edyn,L did not change or declined following PF. Lung resistance increased 19 percent and 41 percent by the end of AF and PF, respectively, in group A. In group B, Ew more than doubled, resulting in a 39 percent increase in Ers. Increases in Ers, Ew, and respiratory flow resistance observed at the time of spinal corrective surgery for kyphoscoliosis may result from rib cage trauma and changes in airway caliber related to microatelectasis and uneven distribution of mechanical properties within the lungs. Spinal correction results in immediate and short-term deterioration of respiratory mechanics measured under anesthesia.
据我们所知,此前尚未有关于脊柱矫正手术对麻醉状态下脊柱侧凸患者的总呼吸力学及其组成部分影响的详细报道。我们研究了13例脊柱侧凸患者;他们的平均(±标准差)年龄为24.7±2.1岁;其中8例患者分别在间隔两周的时间里接受了前路和后路脊柱融合术(分别为AF和PF)(A组),4例仅接受了PF(B组),1例接受了三阶段手术。根据先前描述的方法得出平均总呼吸弹性(Ers)、静态和动态肺弹性(分别为Est,L和Edyn,L)、胸壁弹性(Ew)和肺阻力(RL)。在A组中,AF后Ers和Ew分别增加了39%和58%,PF后分别增加了20%和129%,而PF后Est,L和Edyn,L未发生变化或有所下降。A组中,AF和PF结束时肺阻力分别增加了19%和41%。在B组中,Ew增加了一倍多,导致Ers增加了39%。脊柱侧凸矫正手术时观察到的Ers、Ew和呼吸流阻力增加可能是由于胸廓创伤以及与微肺不张和肺内力学特性分布不均相关的气道口径变化所致。脊柱矫正导致麻醉状态下测量的呼吸力学立即和短期恶化。