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评估和治疗脑卒中后痉挛的功能障碍。

Assessing and treating functional impairment in poststroke spasticity.

机构信息

Institute of Neuroscience and Physiology-Section for Clinical Neuroscience and Rehabilitation, Gothenburg University, Göteborg, Sweden.

出版信息

Neurology. 2013 Jan 15;80(3 Suppl 2):S35-44. doi: 10.1212/WNL.0b013e3182764aa2.

Abstract

Poststroke spasticity (PSS) is associated with significant consequences for a patient's functional status and quality of life. Nonetheless, no uniform definition of spasticity exists that can be utilized across clinical research settings, and difficulties in validating proper assessment tools--both clinical and nonclinical--complicate the ability to evaluate and appropriately treat spasticity. Consequently, the current state of defining, assessing, and treating spasticity requires improved consistency and ongoing validation as clinical research efforts advance. When selecting clinical measures for PSS assessment (e.g., the Modified Ashworth, Tone Assessment, Tardieu, Modified Rankin, and Disability Assessment scales, and the Barthel Index), it is critical to understand the levels of impairment or functional limitation each tool assesses as well as their benefits and limitations. The use of quantitative methods--such as electrophysiologic, biomechanical, and imaging techniques--adjunctive to traditional clinical measures also allows for sensitivity in quantifying the abnormal muscle activity associated with spasticity. In addition to accurate evaluation and assessment of PSS, realistic treatment goal setting for patients as well as family members and caregivers is critical, because it promotes motivation and cooperation as well as proper management of expectations and can favorably affect recovery. Goal attainment scaling has been shown to help organize, focus, and clarify the aims of treatment, thereby enhancing the PSS rehabilitative process. Furthermore, integration of therapeutic modalities and treatment strategies, including both nonpharmacologic intervention and pharmacotherapy, is also important for improved outcomes.

摘要

脑卒中后痉挛(PSS)会对患者的功能状态和生活质量产生重大影响。尽管如此,目前在临床研究环境中还没有一个统一的痉挛定义,这使得验证适当的评估工具(包括临床和非临床工具)变得困难,从而也影响了对痉挛的评估和治疗。因此,在临床研究进展的同时,需要提高定义、评估和治疗痉挛的一致性并持续验证。在选择用于 PSS 评估的临床措施(例如改良 Ashworth、肌张力评估、Tardieu、改良 Rankin 和残疾评估量表以及巴氏指数)时,了解每个工具评估的损伤或功能限制水平以及它们的优缺点非常重要。定量方法的使用——如电生理、生物力学和成像技术——附加于传统的临床措施,也可以提高对痉挛相关异常肌肉活动的定量灵敏度。除了对 PSS 进行准确的评估和评估外,为患者以及家属和护理人员设定现实的治疗目标也至关重要,因为它可以促进动机和合作,以及适当管理期望,并对康复产生有利影响。目标达成量表已被证明有助于组织、关注和阐明治疗目标,从而增强 PSS 康复过程。此外,治疗模式和治疗策略的整合,包括非药物干预和药物治疗,对于改善结果也很重要。

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