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维莫德吉（Erivedge）用于治疗晚期基底细胞癌。

Vismodegib (erivedge) for advanced Basal cell carcinoma.

作者信息

Fellner Chris

出版信息

P T. 2012 Dec;37(12):670-82.

PMID:23319845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3541861/
Abstract

Vismodegib (Erivedge) for advanced basal cell carcinoma.

摘要

维莫德吉（Erivedge）用于治疗晚期基底细胞癌。

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Vismodegib (erivedge) for advanced Basal cell carcinoma.维莫德吉（Erivedge）用于治疗晚期基底细胞癌。
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本文引用的文献

1
Efficacy and safety of vismodegib in advanced basal-cell carcinoma.维莫德吉治疗晚期基底细胞癌的疗效和安全性。
N Engl J Med. 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713.
2
Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.希革替尼（GDC-0449）治疗难治性、局部晚期或转移性实体瘤患者的 I 期临床试验。
Clin Cancer Res. 2011 Apr 15;17(8):2502-11. doi: 10.1158/1078-0432.CCR-10-2745. Epub 2011 Feb 7.
3
Pharmacokinetics of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: the role of alpha-1-acid glycoprotein binding. hedgehog 通路抑制剂维莫德吉（GDC-0449）在局部晚期或转移性实体瘤患者中的药代动力学：α-1-酸性糖蛋白结合的作用。
Clin Cancer Res. 2011 Apr 15;17(8):2512-20. doi: 10.1158/1078-0432.CCR-10-2736. Epub 2011 Feb 7.
4
Focus on Basal cell carcinoma.关注基底细胞癌。
J Skin Cancer. 2011;2011:328615. doi: 10.1155/2011/328615. Epub 2010 Oct 24.
5
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.晚期基底细胞癌中刺猬信号通路的抑制作用。
N Engl J Med. 2009 Sep 17;361(12):1164-72. doi: 10.1056/NEJMoa0905360. Epub 2009 Sep 2.
6
Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449.用刺猬信号通路抑制剂GDC-0449治疗髓母细胞瘤。
N Engl J Med. 2009 Sep 17;361(12):1173-8. doi: 10.1056/NEJMoa0902903. Epub 2009 Sep 2.
7
Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Hedgehog 通路在癌症中的激活机制及其治疗意义。
Trends Pharmacol Sci. 2009 Jun;30(6):303-12. doi: 10.1016/j.tips.2009.03.007. Epub 2009 May 13.
8
Basal cell carcinomas: attack of the hedgehog.基底细胞癌：刺猬信号通路的作用
Nat Rev Cancer. 2008 Oct;8(10):743-54. doi: 10.1038/nrc2503.
9
Guidelines for the management of basal cell carcinoma.基底细胞癌管理指南。
Br J Dermatol. 2008 Jul;159(1):35-48. doi: 10.1111/j.1365-2133.2008.08666.x.
10
Management of nonmelanoma skin cancer in 2007.2007年非黑素瘤皮肤癌的管理
Nat Clin Pract Oncol. 2007 Aug;4(8):462-9. doi: 10.1038/ncponc0883.