Kamimura Kenya, Nomoto Minoru, Aoyagi Yutaka
Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachi 1-757, Chuo-ku, Niigata 951-8122, Japan.
Int J Hepatol. 2012;2012:410781. doi: 10.1155/2012/410781. Epub 2012 Dec 23.
Angiomyolipoma (AML) is a benign mesenchymal tumor that is frequently found in the kidney and, rarely, in the liver. The natural history of hepatic AML has not been clarified, and, because of the similar patterns in imaging studies, such as ultrasonography, computed tomography, and magnetic resonance imaging, some of these tumors have been overdiagnosed as hepatocellular carcinoma in the past. With an increase in the number of case reports showing detailed imaging studies and immunohistochemical staining of the tumor with human melanoma black-45, the diagnostic accuracy is also increasing. In this paper, we focused on the role of noninvasive imaging studies and histological diagnosis showing distinctive characteristics of this tumor. In addition, because several reports have described tumor progression in terms of size, recurrence after surgical resection, metastasis to other organs, and portal thrombosis, we summarized these cases for the management and discussed the indications for the surgical treatment of this tumor.
血管平滑肌脂肪瘤（AML）是一种良性间叶组织肿瘤，常见于肾脏，罕见于肝脏。肝AML的自然病程尚未明确，并且由于超声、计算机断层扫描和磁共振成像等影像学检查中的相似表现，过去一些此类肿瘤被误诊为肝细胞癌。随着越来越多的病例报告展示了详细的影像学检查以及用人类黑色素瘤黑色45对肿瘤进行免疫组织化学染色，诊断准确性也在提高。在本文中，我们重点关注了非侵入性影像学检查和显示该肿瘤独特特征的组织学诊断的作用。此外，由于有几份报告描述了肿瘤在大小、手术切除后复发、转移至其他器官以及门静脉血栓形成方面的进展，我们总结了这些病例以进行管理，并讨论了该肿瘤手术治疗的适应证。
