Department of Dermatology, Allergology and Phlebology, Bremerhaven Reinkenheide Hospital, Bremerhaven, Germany.
J Dtsch Dermatol Ges. 2013 Apr;11(4):309-19. doi: 10.1111/ddg.12031. Epub 2013 Jan 15.
Lichen planus is characterized by lichenoid, polygonal papules with fine white lines, called Wickham striae. Lesions most commonly occur on the limbs and on the dorsal aspect of the trunk. At the same time often leukoplakia of mucous membranes as well as nail disorders are seen. There are numerous variants of lichen planus which can be distinguished from the classical form on the basis of morphology and distribution of the lesions. The typical primary lesion of lichen planus may be replaced by other forms, such as patches, hyperkeratoses, ulcerations, or bullous lesions. Moreover, distribution patterns of these lesions may vary and include erythrodermic, inverse or linear arrangements. In contrast to these numerous clinical features, histologic findings remain characteristic in the variants, so that the diagnosis can be made securely. Differential diagnoses of lichen planus include diverse dermatoses such as bullous pemphigoid or paronychia.
扁平苔藓的特征为苔藓样、多角形丘疹,其上有细的白色线条,称为威克姆纹。皮损最常发生于四肢和躯干的背部。同时常可见黏膜的白色斑块以及甲的病变。扁平苔藓有许多变异型,可根据皮损的形态和分布与经典型相区别。扁平苔藓的典型原发性皮损可能被其他形式替代,如斑块、角化过度、溃疡或大疱性皮损。此外,这些皮损的分布模式可能会发生变化,包括红皮病样、逆向或线状排列。与这些众多的临床表现不同,变异型的组织学表现仍具有特征性,因此可以明确诊断。扁平苔藓的鉴别诊断包括各种皮肤病,如大疱性类天疱疮或甲周皮炎。