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在感染火鸡疱疹病毒O1株的雏鸡中显示带有马立克氏病肿瘤相关表面抗原的细胞。

Demonstration of cells with Marek's disease tumor-associated surface antigen in chicks infected with herpesvirus of turkey, O1 strain.

作者信息

Kitamoto N, Ikuta K, Kato S, Wataki K

出版信息

Biken J. 1979 Dec;22(4):137-42.

PMID:233228
Abstract

The presence of Marek's disease tumor-associated surface antigen (MATSA) was demonstrated by the direct and indirect membrane immunofluorescent tests, in chicks inoculated 7-10 days earlier with herpesvirus of turkeys (HVT), O1 strain. In in vitro cultures of spleen lymphocytes and ovaries obtained from these chicks, MATSA-positive cells were also detected after 1-7 days cultivation. A possible mechanism of protection by HVT vaccine against Marek's disease is proposed.

摘要

通过直接和间接膜免疫荧光试验,在7 - 10天前接种火鸡疱疹病毒(HVT)O1株的雏鸡中证实了马立克氏病肿瘤相关表面抗原(MATSA)的存在。在从这些雏鸡获得的脾脏淋巴细胞和卵巢的体外培养物中,培养1 - 7天后也检测到了MATSA阳性细胞。提出了HVT疫苗预防马立克氏病的一种可能机制。

相似文献

1
Demonstration of cells with Marek's disease tumor-associated surface antigen in chicks infected with herpesvirus of turkey, O1 strain.在感染火鸡疱疹病毒O1株的雏鸡中显示带有马立克氏病肿瘤相关表面抗原的细胞。
Biken J. 1979 Dec;22(4):137-42.
2
Demonstration of Marek's disease tumor-associated surface antigen in chickens infected with nononcogenic Marek's disease virus and herpesvirus of turkeys.在感染非致瘤性马立克氏病病毒和火鸡疱疹病毒的鸡中马立克氏病肿瘤相关表面抗原的展示。
J Natl Cancer Inst. 1978 Sep;61(3):855-7.
3
Effect of maternal immunity against development of Marek's disease and protective ability of vaccine.母源免疫力对马立克氏病发生发展的影响及疫苗的保护能力
Natl Inst Anim Health Q (Tokyo). 1975 Spring;15(1):1-7.
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Turkey herpesvirus infection in chickens: induction of lymphoproliferative lesions and characterization of vaccinal immunity against Marek's disease.鸡的火鸡疱疹病毒感染:淋巴增生性病变的诱导及针对马立克氏病疫苗免疫的特性分析
Avian Dis. 1976 Oct-Dec;20(4):676-92.
5
Precipitating antibody development in chicks experimentally infected with herpes virus of turkey and Marek's disease virus.
J Commun Dis. 1986 Mar;18(1):13-6.
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Marek's disease tumor-associated surface antigen (MATSA) in resistant versus susceptible chickens.抗性与易感鸡体内的马立克氏病肿瘤相关表面抗原(MATSA)
Avian Dis. 1979 Oct-Dec;23(4):831-7.
7
Expression of a putative tumor-associated surface antigen on normal versus Marek's disease virus-transformed lymphocytes.一种假定的肿瘤相关表面抗原在正常淋巴细胞与马立克氏病病毒转化淋巴细胞上的表达。
J Natl Cancer Inst. 1987 Nov;79(5):991-1000.
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Cell-mediated cytotoxicity of lymphocytes from chickens inoculated with herpesvirus of turkey against a Marek's disease lymphoma cell line (MSB-1).接种火鸡疱疹病毒的鸡的淋巴细胞对马立克氏病淋巴瘤细胞系(MSB-1)的细胞介导细胞毒性。
Biken J. 1979 Mar;22(1):11-20.
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Pathogenesis of Marek's disease: early appearance of Marek's disease tumor-associated surface antigen in infected chickens.马立克氏病的发病机制:感染鸡中马立克氏病肿瘤相关表面抗原的早期出现。
J Natl Cancer Inst. 1978 Sep;61(3):849-54.
10
Marek's disease virus and herpesvirus of turkey noninfective to chickens, obtained by repeated in vitro passages.通过多次体外传代获得的对鸡无感染性的马立克氏病病毒和火鸡疱疹病毒。
Biken J. 1979 Sep;22(3):103-7.