University of Pennsylvania, Philadelphia, PA 19104, USA.
BMC Med. 2013 Jan 16;11:11. doi: 10.1186/1741-7015-11-11.
Wilson et al. provided a valuable systematic and meta-analytic review of the Triple P-Positive Parenting program in which they identified substantial problems in the quality of available evidence. Their review largely escaped unscathed after Sanders et al.'s critical commentary. However, both of these sources overlook the most serious problem with the Triple P literature, namely, the over-reliance on positive but substantially underpowered trials. Such trials are particularly susceptible to risks of bias and investigator manipulation of apparent results. We offer a justification for the criterion of no fewer than 35 participants in either the intervention or control group. Applying this criterion, 19 of the 23 trials identified by Wilson et al. were eliminated. A number of these trials were so small that it would be statistically improbable that they would detect an effect even if it were present. We argued that clinicians and policymakers implementing Triple P programs incorporate evaluations to ensure that goals are being met and resources are not being squandered.Please see related articles http://www.biomedcentral.com/1741-7015/10/130 and http://www.biomedcentral.com/1741-7015/10/145.
威尔逊等人对 Triple P-Positive Parenting 计划进行了有价值的系统和荟萃分析评论,他们在其中发现了现有证据质量的实质性问题。在桑德斯等人的批判性评论之后,他们的评论基本上没有受到影响。然而,这两个来源都忽略了 Triple P 文献中最严重的问题,即过度依赖积极但效力明显不足的试验。此类试验特别容易受到偏倚风险和研究者对明显结果的操纵的影响。我们为干预组或对照组不少于 35 名参与者的标准提供了理由。应用此标准,威尔逊等人确定的 23 项试验中有 19 项被排除在外。其中一些试验规模非常小,即使存在效果,它们也极不可能被检测到。我们认为,实施 Triple P 计划的临床医生和政策制定者应进行评估,以确保实现目标并且资源不会被浪费。请参阅相关文章 http://www.biomedcentral.com/1741-7015/10/130 和 http://www.biomedcentral.com/1741-7015/10/145。