miR-122 is more than a shield for the hepatitis C virus genome.
作者信息
García-Sastre Adolfo, Evans Matthew J
机构信息
Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA.
出版信息
Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1571-2. doi: 10.1073/pnas.1220841110. Epub 2013 Jan 16.
Abstract
摘要
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本文引用的文献
1
Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication.miR-122 与 5' 外切核酸酶 Xrn1 在调控丙型肝炎病毒复制中的竞争和非竞争活性。
Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1881-6. doi: 10.1073/pnas.1213515110. Epub 2012 Dec 17.
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The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.miRNA 介导的基因沉默机制：miRISC 内幕观察。
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Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex.Ago2-miR-122 复合物稳定丙型肝炎病毒 RNA。
Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):941-6. doi: 10.1073/pnas.1112263109. Epub 2012 Jan 3.
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MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR.miRNA-122 拮抗 HCV 基因型 1-6 及 HCV 5'UTR 中宿主 RNA 插入或突变导致的疗效降低。
Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4991-6. doi: 10.1073/pnas.1016606108. Epub 2011 Mar 7.
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Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex.通过非常规 microRNA 靶 RNA 复合物对丙型肝炎病毒基因组的 5' 末端核苷酸进行掩蔽。
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The highways and byways of mRNA decay.mRNA 降解的方方面面
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Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA.肝脏特异性微小RNA对丙型肝炎病毒RNA丰度的调控
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