伊朗伊斯法罕育龄妇女的弓形虫感染：一项基于人群的研究。
Toxoplasma gondii infection in women of childbearing age of Isfahan, Iran: A population-based study.
作者信息
Mostafavi Nasser, Ataei Behrooz, Nokhodian Zari, Monfared Leila J, Yaran Majid, Ataie Mehdi, Babak Anahita
机构信息
Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Adv Biomed Res. 2012;1:60. doi: 10.4103/2277-9175.100181. Epub 2012 Aug 28.
BACKGROUND
We conducted an epidemiological survey on seroprevalence of toxoplasma infection in women of childbearing age in Isfahan Province.
MATERIALS AND METHODS
In a cross-sectional study in 2010, 217 women in the age range of 10-50 years were randomly selected. The blood samples examined for the presence of IgG anti-Toxoplasma gondii antibody by a commercial ELISA kit (Dia-Pro, Milan, Italy). Chi-square and Fisher's exact tests were employed to examine the antibody status in different age, marriage, education, and residence groups.
RESULTS
The overall prevalence was 47.5% (103/217). The peak age of infection acquisition was in the range 30-40 years in rural areas and 20-30 years in urban districts. There was no significant association between residence, education, and marriage groups on the one hand and chance of T. gondii infection on the other hand.
CONCLUSIONS
The findings of the study suggest a moderate prevalence of T. gondii infection, but a high prevalence in ages of high reproductive activities.
背景
我们对伊斯法罕省育龄妇女弓形虫感染的血清流行率进行了一项流行病学调查。
材料与方法
在2010年的一项横断面研究中，随机选取了217名年龄在10至50岁之间的女性。使用商用ELISA试剂盒（Dia-Pro，意大利米兰）检测血样中抗弓形虫IgG抗体的存在情况。采用卡方检验和费舍尔精确检验来检查不同年龄、婚姻状况、教育程度和居住群体中的抗体状态。
结果
总体患病率为47.5%（103/217）。农村地区感染获得的高峰年龄在30至40岁之间，城市地区在20至30岁之间。一方面，居住、教育和婚姻群体与另一方面的弓形虫感染几率之间没有显著关联。
结论
该研究结果表明弓形虫感染患病率中等，但在高生育活动年龄段患病率较高。
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