Torrance Helen L, Pistorius Lourens, Voorbij Hieronymus A M, Visser Gerard H A
Perinatal Center, University Medical Center, Utrecht, The Netherlands.
J Matern Fetal Neonatal Med. 2013 May;26(7):728-30. doi: 10.3109/14767058.2013.766685. Epub 2013 Feb 5.
Measurement of amniotic fluid (AF) lactate concentration in complicated pregnancies may provide information on the extent of fetal acidemia. However, normalisation for AF volume may be necessary by calculating the lactate:creatinine (L:C) ratio. We measured these AF parameters and compared them to arterial cord blood lactate in 28 term and 10 preterm pregnancies. Cord blood lactate was not correlated to AF lactate, but was correlated to the L:C ratio in the complete study population (R = 0.54, p = 0.001) and the subgroups. Correlation was strongest in a preterm intrauterine growth restricted subgroup (n = 7, R = 0.83, p = 0.02). The L:C ratio is more accurate in estimating fetal lacticaemia than AF lactate.
测量复杂妊娠中羊水（AF）乳酸浓度可能会提供有关胎儿酸血症程度的信息。然而，可能需要通过计算乳酸：肌酐（L:C）比值来对羊水体积进行标准化。我们测量了这些羊水参数，并将其与28例足月妊娠和10例早产妊娠的脐动脉血乳酸进行了比较。脐血乳酸与羊水乳酸无相关性，但与整个研究人群（R = 0.54，p = 0.001）及其亚组中的L:C比值相关。在早产宫内生长受限亚组（n = 7，R = 0.83，p = 0.02）中相关性最强。在估计胎儿乳酸血症方面，L:C比值比羊水乳酸更准确。
