• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Normal immune responses in systemic sclerosis.

作者信息

Lupoli S, Amlot P, Black C

机构信息

Department of Rheumatology, West Middlesex University Hospital, Isleworth, London, England.

出版信息

J Rheumatol. 1990 Mar;17(3):323-7.

PMID:2332853
Abstract

Cellular and humoral immune responses were assessed in 24 patients with systemic sclerosis and matched controls by immunization with a thymus dependent (TD) antigen, keyhole limpet hemocyanin (KLH), a and thymus independent (TI) antigen, dinitrophenylated Ficoll (DNP-Ficoll). Cell mediated immunity in the patients with systemic sclerosis expressed as delayed cutaneous hypersensitivity to KLH, as well as the primary T dependent and T independent antibody responses were normal. Our findings suggest that there is no generalized defect in the immune responsiveness of patients with systemic sclerosis. There is however evidence that specific defects may occur in certain subsets of patients with systemic sclerosis.

摘要

相似文献

1
Normal immune responses in systemic sclerosis.
J Rheumatol. 1990 Mar;17(3):323-7.
2
Human immune responses in vivo to protein (KLH) and polysaccharide (DNP-Ficoll) neoantigens: normal subjects compared with bone marrow transplant patients on cyclosporine.人体对蛋白质（钥孔戚血蓝蛋白）和多糖（二硝基苯 - 聚蔗糖）新抗原的体内免疫反应：正常受试者与接受环孢素治疗的骨髓移植患者的比较。
Clin Exp Immunol. 1986 Apr;64(1):125-35.
3
Hapten-specific leukocyte migration inhibition. I. Inhibition of cells from animals immunized with DNP-KLH by epsilon-DNP-L-lysine Ficoll.半抗原特异性白细胞游走抑制。I. ε-二硝基苯-L-赖氨酸-聚蔗糖对用二硝基苯-钥孔戚血蓝蛋白免疫的动物细胞的抑制作用。
J Immunol. 1977 Apr;118(4):1335-7.
4
Lack of specific antibody response in common variable immunodeficiency (CVID) associated with failure in production of antigen-specific memory T cells. MRC Immunodeficiency Group.常见变异型免疫缺陷（CVID）中缺乏特异性抗体反应，与抗原特异性记忆T细胞产生失败相关。医学研究委员会免疫缺陷研究小组。
Clin Exp Immunol. 1997 Apr;108(1):9-13. doi: 10.1046/j.1365-2249.1997.d01-993.x.
5
Primary in situ immune response in popliteal lymph nodes and spleen of mice after subcutaneous immunization with thymus-dependent or thymus-independent (type 1 and 2) antigens.用胸腺依赖性或胸腺非依赖性（1型和2型）抗原皮下免疫小鼠后，其腘窝淋巴结和脾脏中的原发性原位免疫反应。
Anat Rec. 1989 Feb;223(2):152-7. doi: 10.1002/ar.1092230206.
6
Induction of an immune response to keyhole-limpet hemocyanin in surgical patients with anergy.在无反应性的外科手术患者中诱导对钥孔戚血蓝蛋白的免疫反应。
Surgery. 1990 Apr;107(4):442-8.
7
Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men.年龄和身体活动对男性体内主要抗体及T细胞介导反应的影响。
J Appl Physiol (1985). 2004 Aug;97(2):491-8. doi: 10.1152/japplphysiol.01404.2003.
8
Immunization responses in rheumatoid arthritis patients treated with rituximab: results from a controlled clinical trial.接受利妥昔单抗治疗的类风湿关节炎患者的免疫反应：一项对照临床试验的结果。
Arthritis Rheum. 2010 Jan;62(1):64-74. doi: 10.1002/art.25034.
9
The in situ immune response in popliteal lymph nodes of mice after macrophage depletion. Differential effects of macrophages on thymus-dependent and thymus-independent immune responses.巨噬细胞耗竭后小鼠腘窝淋巴结中的原位免疫反应。巨噬细胞对胸腺依赖性和非胸腺依赖性免疫反应的不同影响。
Immunobiology. 1990 Jun;180(4-5):395-404. doi: 10.1016/S0171-2985(11)80301-3.
10
B-cell subsets responsive to fluorescein-conjugated antigens. III. Differential effect of E. Coli lipopolysaccharide on T-dependent and T-independent responses in vivo.对荧光素偶联抗原产生反应的B细胞亚群。III. 大肠杆菌脂多糖对体内T细胞依赖性和T细胞非依赖性反应的不同影响。
Immunology. 1979 Nov;38(3):519-27.