Faculty of Health and Life Sciences, Center of Superior Studies of Maceió, CESMAC, Maceió, AL, Brazil.
J Appl Oral Sci. 2012 Nov-Dec;20(6):607-12. doi: 10.1590/s1678-77572012000600004.
In order to prolong the clinical longevity of resilient denture relining materials and reduce plaque accumulation, incorporation of antimicrobial agents into these materials has been proposed. However, this addition may affect their properties.
This study evaluated the effect of the addition of antimicrobial agents into one soft liner (Soft Confort, Dencril) on its peel bond strength to one denture base (QC 20, Dentsply).
Acrylic specimens (n=9) were made (75x10x3 mm) and stored in distilled water at 37 ºC for 48 h. The drug powder concentrations (nystatin 500,000 U--G2; nystatin 1,000,000 U--G3; miconazole 125 mg--G4; miconazole 250 mg--G5; ketoconazole 100 mg - G6; ketoconazole 200 mg--G7; chlorhexidine diacetate 5%--G8; and 10% chlorhexidine diacetate--G9) were blended with the soft liner powder before the addition of the soft liner liquid. A group (G1) without any drug incorporation was used as control. Specimens (n=9) (75x10x6 mm) were plasticized according to the manufacturers' instructions and stored in distilled water at 37 ºC for 24 h. Relined specimens were then submitted to a 180-degree peel test at a crosshead speed of 10 mm/min. Data (MPa) were analyzed by analysis of variance (α=0.05) and the failure modes were visually classified.
No significant difference was found among experimental groups (p=0.148). Cohesive failure located within the resilient material was predominantly observed in all tested groups.
Peel bond strength between the denture base and the modified soft liner was not affected by the addition of antimicrobial agents.
为了延长弹性义齿衬垫材料的临床寿命并减少菌斑堆积,有人提议在这些材料中加入抗菌剂。然而,这种添加可能会影响它们的性能。
本研究评估了将一种软衬材料(Soft Confort,Dencril)中的抗菌剂添加到一种义齿基托(QC 20,Dentsply)中对其剥离粘结强度的影响。
制作了(75x10x3mm)丙烯酸样本(n=9),并将其储存在 37°C 的蒸馏水中 48 小时。药物粉末浓度(nystatin 500,000 U-G2;nystatin 1,000,000 U-G3;miconazole 125 mg-G4;miconazole 250 mg-G5;ketoconazole 100 mg-G6;ketoconazole 200 mg-G7;chlorhexidine diacetate 5%-G8;10% chlorhexidine diacetate-G9)在加入软衬液之前与软衬粉混合。一组(G1)不加入任何药物作为对照。根据制造商的说明对(75x10x6mm)样本进行塑化,并将其储存在 37°C 的蒸馏水中 24 小时。然后将衬里样本在 180°下以 10mm/min 的十字头速度进行剥离测试。用方差分析(α=0.05)分析数据(MPa),并对失效模式进行视觉分类。
实验各组之间无显著性差异(p=0.148)。在所有测试组中,主要观察到位于弹性材料内的内聚性破坏。
义齿基托和改性软衬之间的剥离粘结强度不受抗菌剂添加的影响。