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含二氧化硅纳米颗粒的义齿软衬材料的抗真菌活性及一些表面特性

Antifungal Activities and Some Surface Characteristics of Denture Soft Liners Containing Silicon Dioxide Nanoparticles.

作者信息

Gad Mohammed M, Bahgat Hala A, Edrees Mohamed F, Alhumaidan Abdulkareem, Khan Soban Qadir, Ayad Neveen M

机构信息

Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Department of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

J Int Soc Prev Community Dent. 2022 Jan 29;12(1):109-116. doi: 10.4103/jispcd.JISPCD_286_21. eCollection 2022 Jan-Feb.

Abstract

OBJECTIVE

This study aimed at determining the influence of adding silicon dioxide nanoparticles (nano-SiO) to soft relining materials on adhesion, surface roughness, and contact angle.

MATERIALS AND METHODS

Eighty heat-polymerized acrylic resin disks were constructed and relined by using auto-polymerized acrylic soft liners (COE-SOFT, GC Co., Tokyo, Japan). The specimens were categorized into two groups according to the tests conducted. Group A was composed of 40 specimens for evaluating antifungal activity, and Group B was composed of 40 specimens for testing surface roughness and contact angle. Each group was subcategorized into four subgroups ( = 10) according to the concentration of nano-SiO added to the soft-liner powder: control, 0.25%, 0.5%, and 1.0% by weight. The colony forming unit (CFU) was used to assess count. A profilometer was used to measure the surface roughness values (Ra; μm). The sessile drop method was used to evaluate the contact angle () by using a goniometer. Analysis of variance and Tukey's post hoc tests (α = 0.05) were used for the data analysis.

RESULTS

In comparison with the unmodified group, the 0.25% and the 0.5% nano-SiO groups exhibited significantly lower counts ( 0.001), surface roughness ( 0.001), and contact angles ( 0.001). The exception was the 1% group, which exhibited higher count, surface roughness, and contact angles than lower-concentration nano-SiO groups; however, these values in the 1% group were still less than their respective values in the control group.

CONCLUSION

The addition of 0.25% and 0.5% nano-SiO to an auto-polymerized acrylic soft liner decreased adhesion, surface roughness, and contact angle.

摘要

目的

本研究旨在确定向软衬材料中添加二氧化硅纳米颗粒(纳米SiO₂)对附着力、表面粗糙度和接触角的影响。

材料与方法

制作80个热聚合丙烯酸树脂圆盘,并用自聚合丙烯酸软衬材料(COE-SOFT,日本东京GC公司)进行衬里。根据所进行的测试,将标本分为两组。A组由40个用于评估抗真菌活性的标本组成,B组由40个用于测试表面粗糙度和接触角的标本组成。根据添加到软衬材料粉末中的纳米SiO₂浓度,每组再细分为四个亚组(n = 10):对照组、0.25%、0.5%和1.0%(重量)。采用菌落形成单位(CFU)来评估计数。使用轮廓仪测量表面粗糙度值(Ra;μm)。采用静滴法,使用测角仪评估接触角(θ)。采用方差分析和Tukey事后检验(α = 0.05)进行数据分析。

结果

与未改性组相比,0.25%和0.5%纳米SiO₂组的CFU计数(P < 0.001)、表面粗糙度(P < 0.001)和接触角(P < 0.001)均显著降低。例外的是1%组,其CFU计数、表面粗糙度和接触角均高于低浓度纳米SiO₂组;然而,1%组的这些值仍低于对照组的相应值。

结论

向自聚合丙烯酸软衬材料中添加0.25%和0.5%的纳米SiO₂可降低CFU附着力、表面粗糙度和接触角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3617/8896586/4f6a43fe580e/JISPCD-12-109-g001.jpg

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