Bakhshayeshkaram Mehrdad, Saidi Bahareh, Tabarsi Payam, Zahirifard Soheila, Ghofrani Mishka
Department of Radiology, Pediatric Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Radiol. 2011 Dec;8(4):230-4. doi: 10.5812/iranjradiol.4554. Epub 2011 Dec 25.
Swine influenza (H1N1) is a very contagious respiratory infection and World Health Organization (WHO) has raised the alert level to phase 6 (pandemic). The study of clinical and laboratory manifestations as well as radiologic imaging findings helps in its early diagnosis.
The aim of this study was to evaluate the imaging findings of patients with documented H1N1 infection referred to our center.
Thirty-one patients (16 men) with documented H1N1 infection were included in our study. The initial radiography obtained from the patients was reviewed regarding pattern (consolidation, ground glass, nodules and reticulation), distribution (focal, multifocal, and diffuse) and the lung zones involved. Computed tomography (CT) scans were also reviewed for the same abnormalities. The patient files were studied for their possible underlying diseases.
The mean age was 37.97 ± 13.9 years. Seventeen (54.8%) patients had co-existing condition (eight respiratory, five cardiovascular, two immunodeficiency, two cancer, four others). Twelve (38.7%) patients required intensive care unit (ICU) admission. Five (16.1%) patients died. (25.8%) had normal initial radiographs. The most common abnormality was consolidation (12/31; 38.7%) in the peripheral region (11/31; 35.5%) followed by peribronchovascular areas (10/31; 32.3%) which was most commonly observed in the lower zone. The patients admitted to the ICU were more likely to have two or more lung zones involved (P = 0.005).
In patients with the novel swine flu infection, the most common radiographic abnormality observed was consolidation in the lower lung zones. Patients admitted to ICU were more likely to have two or more lung zones involved.
甲型H1N1流感是一种极具传染性的呼吸道感染疾病，世界卫生组织（WHO）已将警戒级别提升至6级（大流行）。对临床表现、实验室检查结果以及影像学检查结果的研究有助于早期诊断。
本研究旨在评估转诊至我院确诊为H1N1感染患者的影像学表现。
本研究纳入31例确诊为H1N1感染的患者（16例男性）。回顾患者最初的X线胸片，观察其影像类型（实变、磨玻璃影、结节及网状影）、分布情况（局灶性、多灶性及弥漫性）以及受累肺区。同时也回顾了计算机断层扫描（CT）图像，观察是否存在同样的异常表现。研究患者病历，了解其可能存在的基础疾病。
患者的平均年龄为37.97±13.9岁。17例（54.8%）患者存在基础疾病（8例呼吸系统疾病、5例心血管系统疾病、2例免疫缺陷病、2例癌症、4例其他疾病）。12例（38.7%）患者需要入住重症监护病房（ICU）。5例（16.1%）患者死亡。25.8%的患者最初X线胸片正常。最常见的异常表现为外周区域实变（12/31；38.7%），其次为支气管血管周围区域实变（10/31；32.3%），最常出现在下肺区（11/31；35.5%）。入住ICU的患者更易出现两个或以上肺区受累（P = 0.005）。
在新型甲型H1N1流感感染患者中，最常见的影像学异常表现为下肺区实变。入住ICU的患者更易出现两个或以上肺区受累。
