Division of Neonatology, Department of Pediatrics, Innsbruck Medical University, Innsbruck, Austria.
Acta Paediatr. 2013 May;102(5):e235-8. doi: 10.1111/apa.12165. Epub 2013 Jan 31.
Early sudden unexpected death in infancy (ESUDI) is a rare cause of death occurring in newborns during the first hours of life. Our aim was to find additional data for the identification of risk factors and establishment of prevention strategies.
We describe three cases of ESUDI and give an overview of the literature.
ESUDI was observed in term babies with normal birth weight after good postnatal adaptation within the first four hours of life. Maternal age was between 29 and 36 years, mothers were primiparous and of normal weight. All three events occurred during unobserved early skin-to-skin contact. Autopsy and post-mortem metabolic screening revealed no cause of death. A search of the MEDLINE and Web of Science (Thomson Reuters) databases brought to light 132 cases of ESUDI reported in the literature from 1985 to 2012. Concurrent with our observations, first parity and unobserved early skin-to-skin contact seem to be prime predictors of ESUDI. Other pre-described risk factors such as mode of delivery, birth weight, mother's age and body mass index were not seen in our patients.
Close observation during the first hours of life is essential and can be life-saving, especially during early skin-to-skin contact.
婴儿早期突发意外死亡（ESUDI）是一种罕见的死因，发生在新生儿生命的头几个小时内。我们的目的是寻找额外的数据，以确定危险因素并制定预防策略。
我们描述了 3 例 ESUDI 病例，并对文献进行了综述。
ESUDI 发生在足月出生体重正常的婴儿中，出生后适应良好，在生命的头 4 小时内。母亲年龄在 29 至 36 岁之间，均为初产妇，体重正常。所有 3 例均发生在未观察到的早期皮肤接触期间。尸检和死后代谢筛查未发现死因。通过 MEDLINE 和 Web of Science（Thomson Reuters）数据库检索，从 1985 年至 2012 年在文献中发现了 132 例 ESUDI 报告。与我们的观察结果一致，初产和未观察到的早期皮肤接触似乎是 ESUDI 的主要预测因素。其他已描述的危险因素，如分娩方式、出生体重、母亲年龄和体重指数，在我们的患者中并未出现。
生命最初几小时的密切观察至关重要，可以救命，特别是在早期皮肤接触期间。
