Cell Host Microbe. 2013 Jan 16;13(1):1-3. doi: 10.1016/j.chom.2013.01.002.
A paper in this issue by Ogawa et al. (2013) shows that HSV-2-infected keratinocytes in human skin explants release a protein that enhances HIV-1 infection of Langerhans cells in vitro. This may explain the in vivo observation that HSV-2 infection facilitates HIV-1 acquisition.
本文由 Ogawa 等人(2013)撰写,指出人类皮肤标本中的单纯疱疹病毒 2 感染的角质形成细胞释放一种蛋白,可增强 HIV-1 对体外朗格汉斯细胞的感染。这也许可以解释单纯疱疹病毒 2 感染促进 HIV-1 获得的体内观察结果。