Department of Biology, McGill University Montreal, QC, Canada.
Front Plant Sci. 2013 Jan 11;3:308. doi: 10.3389/fpls.2012.00308. eCollection 2012.
The secretory pathway of eukaryotic cells has an elaborated set of endomembrane compartments involved in the synthesis, modification, and sorting of proteins and lipids. The secretory pathway in plant cells shares many features with that in other eukaryotic cells but also has distinct characteristics important for fundamental cell and developmental processes and for proper immune responses. Recently, there has been evidence that the remodeling of this pathway, and often the formation of viral-induced organelles, play an important role in viral replication and spread. The modification of the host secretory pathway seems to be a common feature among most single-stranded positive ss(+)RNA and even some DNA viruses. In this review, we will present the recent advances in the understanding of the organization and dynamics of the plant secretory pathway and the molecular regulation of membrane trafficking in the pathway. We will also discuss how different plant viruses may interact with the host secretory pathway for their efficient replication and spread, with a focus on tobacco mosaic virus and turnip mosaic virus.
真核细胞的分泌途径有一套精细的内膜结构，参与蛋白质和脂质的合成、修饰和分拣。植物细胞的分泌途径与其他真核细胞有许多共同特征，但也有一些独特的特征，这些特征对于基本的细胞和发育过程以及适当的免疫反应很重要。最近的证据表明，该途径的重塑，通常还有病毒诱导细胞器的形成，在病毒复制和传播中起着重要作用。宿主分泌途径的改变似乎是大多数单链正 ss(+)RNA 甚至一些 DNA 病毒的共同特征。在这篇综述中，我们将介绍近年来对植物分泌途径的组织和动态以及途径中膜运输分子调控的理解的最新进展。我们还将讨论不同的植物病毒如何与宿主分泌途径相互作用以实现有效的复制和传播，重点介绍烟草花叶病毒和芜菁花叶病毒。
