Department of Psychiatry and Behavioral Sciences, School of Medicine, Duke University Medical Center, Box 3903, Durham, NC 27710, USA.
J Psychiatr Res. 2013 Apr;47(4):555-63. doi: 10.1016/j.jpsychires.2012.12.009. Epub 2013 Jan 19.
To examine prevalences of substance use disorders (SUD) and comprehensive patterns of comorbidities among psychiatric patients ages 18-64 years (N = 40,099) in an electronic health records (EHR) database.
DSM-IV diagnoses among psychiatric patients in a large university system were systematically captured: SUD, anxiety (AD), mood (MD), personality (PD), adjustment, childhood-onset, cognitive/dementia, dissociative, eating, factitious, impulse-control, psychotic (schizophrenic), sexual/gender identity, sleep, and somatoform diagnoses. Comorbidities and treatment types among patients with a SUD were examined.
Among all patients, 24.9% (n = 9984) had a SUD, with blacks (35.2%) and Hispanics (32.9%) showing the highest prevalence. Among patients with a SUD, MD was prevalent across all age groups (50.2-56.6%). Patients aged 18-24 years had elevated odds of comorbid PD, adjustment, childhood-onset, impulse-control, psychotic, and eating diagnoses. Females had more PD, AD, MD, eating, and somatoform diagnoses, while males had more childhood-onset, impulse-control, and psychotic diagnoses. Blacks had greater odds than whites of psychotic and cognitive/dementia diagnoses, while whites exhibited elevated odds of PA, AD, MD, childhood-onset, eating, somatoform, and sleep diagnoses. Women, blacks, and Native American/multiple-race adults had elevated odds of using inpatient treatment; men, blacks, and Hispanics had increased odds of using psychiatric emergency care. Comorbid MD, PD, adjustment, somatoform, psychotic, or cognitive/dementia diagnoses increased inpatient treatment.
Patients with a SUD, especially minority members, use more inpatient or psychiatric emergency care than those without. Findings provide evidence for research on understudied diagnoses and underserved populations in the real-world clinical settings.
在电子健康记录(EHR)数据库中检查 18-64 岁精神病患者(N=40099)的物质使用障碍(SUD)患病率和综合共病模式。
在一个大型大学系统中,对精神病患者的 DSM-IV 诊断进行了系统采集:SUD、焦虑症(AD)、心境障碍(MD)、人格障碍(PD)、适应障碍、儿童起病、认知/痴呆、分离性障碍、进食障碍、躯体变形障碍、冲动控制障碍、精神病(精神分裂症)、性/性别认同障碍、睡眠障碍和躯体形式障碍诊断。检查了患有 SUD 的患者的共病和治疗类型。
在所有患者中,有 24.9%(n=9984)患有 SUD,黑人(35.2%)和西班牙裔(32.9%)的患病率最高。在患有 SUD 的患者中,MD 在所有年龄组中都很常见(50.2-56.6%)。18-24 岁的患者患 PD、适应障碍、儿童起病、冲动控制障碍、精神病和进食障碍的几率较高。女性 PD、AD、MD、进食障碍和躯体形式障碍的诊断更多,而男性则有更多的儿童起病、冲动控制和精神病的诊断。黑人患精神病和认知/痴呆的几率高于白人,而白人则表现出更高的 PA、AD、MD、儿童起病、进食障碍、躯体形式障碍和睡眠障碍的几率。女性、黑人以及美国原住民/多种族成年人使用住院治疗的几率较高;男性、黑人以及西班牙裔使用精神科急诊治疗的几率较高。合并 MD、PD、适应障碍、躯体形式障碍、精神病或认知/痴呆的诊断会增加住院治疗。
患有 SUD 的患者,特别是少数族裔患者,比没有 SUD 的患者更倾向于使用住院或精神科急诊治疗。研究结果为真实临床环境中对研究不足的诊断和服务不足的人群进行研究提供了证据。