分析来自健康猪的扁桃体和心脏中的猪细小病毒，揭示了德国的高流行率和遗传多样性。
Analysis of porcine parvoviruses in tonsils and hearts from healthy pigs reveals high prevalence and genetic diversity in Germany.
机构信息
Institute of Animal Hygiene and Veterinary Public Health, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 1, 04103 Leipzig, Germany.
出版信息
Arch Virol. 2013 Jun;158(6):1173-80. doi: 10.1007/s00705-013-1603-0. Epub 2013 Jan 22.
In the present study, tonsils and hearts from 100 pigs were collected in a German slaughterhouse in 2010 and tested for porcine parvoviruses (PPV, PPV2, PPV3 and PPV4). PPV was observed in 60 of 100 hearts and 61 of 100 tonsils, and PPV2 was observed in 55 of 100 hearts and 78 of 100 tonsils. PPV3 and PPV4 were found in 20 and 7, respectively, of the 100 tonsils tested, but not in the heart samples. Positive samples of PPV, PPV2 and PPV3 were analyzed by nucleotide sequencing, and phylogenetic analysis revealed at least two distinct lineages for each virus in the German samples. The high detection rate of PPV, PPV2 and PPV3 in healthy animals and their genetic diversity highlights the importance of continuous monitoring of these viruses and their zoonotic potential.
在本研究中，2010 年在一家德国屠宰场采集了 100 头猪的扁桃体和心脏，并对其进行了猪细小病毒（PPV、PPV2、PPV3 和 PPV4）检测。结果发现，在 100 个心脏中有 60 个和 100 个扁桃体中有 61 个检测到了 PPV，在 100 个心脏中有 55 个和 100 个扁桃体中有 78 个检测到了 PPV2。在检测的 100 个扁桃体样本中分别发现了 20 个和 7 个 PPV3 和 PPV4，但在心脏样本中没有发现。对 PPV、PPV2 和 PPV3 的阳性样本进行了核苷酸测序分析，系统进化分析显示德国样本中的每种病毒至少存在两个不同的谱系。在健康动物中检测到 PPV、PPV2 和 PPV3 的高检出率及其遗传多样性突出表明，必须持续监测这些病毒及其人畜共患潜力。
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