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[喜得镇在内耳病理学中的应用]

[Hydergine in pathology of the inner ear].

作者信息

Jiménez-Cervantes Nicolás J, Amorós Rodríguez L M

出版信息

An Otorrinolaringol Ibero Am. 1990;17(1):85-98.

PMID:2334027
Abstract

There have been treated a total of 20 patients with troubles on the cochlear compartment and/or vestibular level which have been clinically expressed by a perceptive hypoacusia, tinnitus and rotatory vertigo. The final evaluation is referred to 17 patients, since three patients do not appear for control. All patients were treated only with Hydergine, on doses of 30 drops thrice daily, which is the equivalent to 4.5 mg/day of active substance. This treatment remained unaltered till the end of the last control. Controls have been effected after 30, 60 and 90 days of starting the treatment. In each control there was evaluated the subjective improvement of vertigo, tinnitus and hypoacusia when effecting to all patients by means of liminar- supraliminar- and automaticaudiometry, impedancimetry, T one-decay-test and electrooculonistagmography. The most meliorated symptomatology was vertigo, with a global improvement of 93.7 per cent on the treated patients. Tinnitus improve by 57.1 per cent and hypoacusia by 20 per cent. There is a total correspondence between the subjective data furnished by the patients and the objective tests carried out in the successive controls.

摘要

共有20例耳蜗区和/或前庭水平出现问题的患者接受了治疗,这些问题在临床上表现为感音性听力减退、耳鸣和旋转性眩晕。最终评估涉及17例患者,因为有3例患者未前来复诊。所有患者仅接受喜得镇治疗,剂量为每日三次,每次30滴,相当于活性物质4.5毫克/天。该治疗方案直至最后一次复诊结束时均未改变。在开始治疗30天、60天和90天后进行了复诊。每次复诊时,通过阈上听阈和自动听力测定、声阻抗测量、T音衰变试验和眼震电图对所有患者进行评估,以评价眩晕、耳鸣和听力减退的主观改善情况。改善最明显的症状是眩晕,接受治疗的患者总体改善率为93.7%。耳鸣改善了57.1%,听力减退改善了20%。患者提供的主观数据与后续复诊中进行的客观测试结果完全一致。

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